{"id":"W2170634666","doi":"10.1038/ng.286","title":"DNA methylation profiles in monozygotic and dizygotic twins","year":2009,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":670,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression","keywords":"Biology; DNA methylation; Epigenetics; Genetics; Monozygotic twin; CpG site; Buccal swab; Epigenomics; Twin study; Heritability; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002660098,0.0001737915,0.0003721767,0.001200092,0.0004081921,0.000450418,0.0002784448,0.0003740754,0.001515581],"category_scores_gemma":[0.001790385,0.0002427484,0.0002428554,0.000625237,0.0001970155,0.00009926152,0.0004642199,0.0003582693,0.0002571371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002337571,"about_ca_system_score_gemma":0.000152987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005083147,"about_ca_topic_score_gemma":0.004192358,"domain_scores_codex":[0.9997054,0.00007235134,0.00002853352,0.00008072083,0.00006130718,0.00005175922],"domain_scores_gemma":[0.9995131,0.0001107717,0.00007530759,0.000056555,0.00009158761,0.0001526374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005950818,0.0002701101,0.600831,0.0000962593,0.0005050182,0.001366784,0.004358691,0.0001668208,0.3687817,0.0008183523,0.000493484,0.01636096],"study_design_scores_gemma":[0.00003127415,0.0003520283,0.9815587,0.00001107438,0.0001688179,0.00337072,0.0009796391,0.000332247,0.01213958,0.0002661743,0.0007707769,0.00001900792],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993937,0.0001033169,0.00007804587,0.000009939154,0.000004695502,0.000002930858,0.0001611587,0.000001802035,0.0002444736],"genre_scores_gemma":[0.9982831,0.0001163909,0.0001742998,0.00002330085,0.000003211866,0.000007237988,0.0002968072,0.000007834818,0.001087834],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005083147,"threshold_uncertainty_score":0.0101071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007357303786291861,"score_gpt":0.2684199468283932,"score_spread":0.2610626430421014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}