{"id":"W2170650990","doi":"10.1095/biolreprod.109.083196","title":"Assessing the Role of Claudins in Maintaining the Integrity of Epididymal Tight Junctions Using Novel Human Epididymal Cell Lines1","year":2010,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal; McGill University; Royal Victoria Hospital; Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research","keywords":"Claudin; Biology; Tight junction; Occludin; Adherens junction; Epididymis; Cell biology; Sperm; Gene knockdown; Context (archaeology); Cadherin; Cell culture; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005802239,0.0004044169,0.000366581,0.0003935868,0.0002981724,0.0004682114,0.0004528737,0.0003881535,0.001403202],"category_scores_gemma":[0.0003707263,0.0001723522,0.000302443,0.0004036766,0.0001977693,0.0003150483,0.0002517673,0.0005551581,0.0005043124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002303564,"about_ca_system_score_gemma":0.0001844631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007631356,"about_ca_topic_score_gemma":0.001316875,"domain_scores_codex":[0.9997236,0.00004965546,0.00003696233,0.00005548746,0.0000944202,0.00003985973],"domain_scores_gemma":[0.9997459,0.00007636743,0.00003974727,0.00004208928,0.00006302918,0.00003282599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008083836,0.00005611661,0.0006664975,0.00006911939,0.000009702457,0.00007412113,0.00003650801,0.0000465785,0.9976773,0.0001051301,0.00006112687,0.001116929],"study_design_scores_gemma":[0.00003460051,0.001093436,0.01433764,0.00001749564,0.0001141815,0.0008102559,0.0001003661,0.001582232,0.9728647,0.00005034809,0.008981598,0.0000129962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9607804,0.008967139,0.02540286,0.0001544891,0.00007943012,0.0002514728,0.002351476,0.0001481859,0.001864456],"genre_scores_gemma":[0.9568261,0.006855698,0.02337899,0.0001120158,0.00003961652,0.0002624569,0.008121786,0.00006835297,0.00433505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001403202,"threshold_uncertainty_score":0.004694223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07687977076913333,"score_gpt":0.3509599403594817,"score_spread":0.2740801695903484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}