{"id":"W2170699724","doi":"10.1093/cid/cis338","title":"Fidaxomicin Preserves the Intestinal Microbiome During and After Treatment of Clostridium difficile Infection (CDI) and Reduces Both Toxin Reexpression and Recurrence of CDI","year":2012,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":305,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre; University of Calgary; Alberta Health Services","funders":"U.S. Public Health Service; Viropharma","keywords":"Fidaxomicin; Clostridium difficile; Vancomycin; Medicine; Microbiology; Feces; Gastroenterology; Internal medicine; Antibiotics; Microbiome; Clostridium; Clostridium difficile toxin A; Antibiotic-associated diarrhea; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002722011,0.0002379099,0.0005521101,0.000133321,0.000128257,0.00002909431,0.00004981664,0.0001339756,0.00005397033],"category_scores_gemma":[0.0009003207,0.0001562645,0.0001488326,0.0002058495,0.0008047468,0.0001362095,0.0001859615,0.0002039456,0.000001744067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005770947,"about_ca_system_score_gemma":0.00008341605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001964252,"about_ca_topic_score_gemma":0.00002035489,"domain_scores_codex":[0.9982418,0.0002267139,0.0006423536,0.0003672715,0.000194069,0.0003278315],"domain_scores_gemma":[0.9981155,0.0008638217,0.0002292533,0.0003237666,0.0001178277,0.0003497832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009210311,0.001862153,0.8877513,0.0004388264,0.0001089274,0.000006446231,0.000192538,9.567178e-7,0.09912278,0.000007101349,0.0001345294,0.009453417],"study_design_scores_gemma":[0.001954823,0.002014349,0.7994888,0.0004706297,0.0003054144,0.00006291131,0.00008572003,0.00003560347,0.1952142,0.0000196669,0.0002098631,0.0001380071],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896678,0.009201747,0.00000287778,0.0001751503,0.0001492019,0.0006023132,0.0000819811,0.00003564334,0.00008333629],"genre_scores_gemma":[0.9910221,0.008432338,0.00001507549,0.00001660113,0.0003275321,0.00005599766,0.00001518176,0.00002008474,0.00009505983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09609146,"threshold_uncertainty_score":0.6372283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03848350234336761,"score_gpt":0.3537053129646918,"score_spread":0.3152218106213241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}