{"id":"W2170796164","doi":"10.2166/wqrj.2002.042","title":"Induction of Vitellogenin and Histological Effects in Wild Fathead Minnows from a Lake Experimentally Treated with the Synthetic Estrogen, Ethynylestradiol","year":2002,"lang":"en","type":"article","venue":"Water Quality Research Journal","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Fisheries and Oceans Canada","funders":"Health Canada","keywords":"Vitellogenin; Vitellogenesis; Pimephales promelas; Estrogen; Internal medicine; Endocrinology; Biology; Yolk; Population; Bioassay; Andrology; Fish <Actinopterygii>; Medicine; Ecology; Fishery; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001462997,0.0001251213,0.0002038685,0.00007582875,0.0001436226,0.00003371928,0.0001786849,0.0001480302,0.00008185241],"category_scores_gemma":[0.0002485532,0.00006154559,0.00005481869,0.00008594315,0.0008460045,0.00001023186,0.00006127486,0.0003934139,0.000004582813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002931743,"about_ca_system_score_gemma":0.00002194581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008729509,"about_ca_topic_score_gemma":0.00006902398,"domain_scores_codex":[0.9974022,0.001483696,0.0002582646,0.0002960447,0.0002434294,0.0003163787],"domain_scores_gemma":[0.9993683,0.0001103528,0.00007473463,0.0002575493,0.0001034106,0.0000856517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004705418,0.0001781312,0.0197026,0.000007555333,0.0001195606,0.00001838272,0.001094125,0.000003419904,0.9759079,0.00003221367,0.0002485517,0.002217018],"study_design_scores_gemma":[0.0009209801,0.001397164,0.02884491,0.00003017211,0.00001531364,0.0003292899,0.0009037625,0.00001141046,0.9660197,0.0002307885,0.001176112,0.000120377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958316,0.002335913,0.00006769199,0.001398514,0.00002703174,0.000226435,0.000006925199,0.000002796343,0.0001030647],"genre_scores_gemma":[0.99916,0.0002426133,0.0001801126,0.00003686218,0.0001204103,0.00001731724,0.0000148368,0.000008464088,0.0002193706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009888173,"threshold_uncertainty_score":0.3117139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08357468697900058,"score_gpt":0.3458888599221028,"score_spread":0.2623141729431022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}