{"id":"W2170796164","doi":"10.2166/wqrj.2002.042","title":"Induction of Vitellogenin and Histological Effects in Wild Fathead Minnows from a Lake Experimentally Treated with the Synthetic Estrogen, Ethynylestradiol","year":2002,"lang":"en","type":"article","venue":"Water Quality Research Journal","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Fisheries and Oceans Canada","funders":"Health Canada","keywords":"Vitellogenin; Vitellogenesis; Pimephales promelas; Estrogen; Internal medicine; Endocrinology; Biology; Yolk; Population; Bioassay; Andrology; Fish <Actinopterygii>; Medicine; Ecology; Fishery; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001354151,0.0003011663,0.0002513967,0.0003240272,0.0003435157,0.0003070441,0.0001867416,0.0002858737,0.001163873],"category_scores_gemma":[0.0002295964,0.0002342142,0.0001811104,0.000159018,0.0004568297,0.000203722,0.0002579198,0.0002528534,0.0001559294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009544839,"about_ca_system_score_gemma":0.0004905784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008714675,"about_ca_topic_score_gemma":0.03710524,"domain_scores_codex":[0.9998605,0.00001404435,0.00001047149,0.00004057345,0.00003431773,0.00004001793],"domain_scores_gemma":[0.9998116,0.00001951352,0.0000600759,0.00001155823,0.00004233335,0.00005502717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007241401,0.0000534826,0.01001084,0.00003309141,0.00001073258,0.00006444217,0.0001328827,0.00003093488,0.9881968,0.00001170715,0.00002638096,0.0007045424],"study_design_scores_gemma":[0.00008350042,0.005359303,0.4281215,0.000008483659,0.00005865186,0.0001906505,0.0007541193,0.0004375648,0.5633797,0.00003036386,0.001558808,0.00001737816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995937,0.00004182157,0.00007715322,0.000009711412,0.000002147871,0.000009995929,0.0001192792,0.000005936937,0.0001404047],"genre_scores_gemma":[0.9957359,0.00008945359,0.0005927316,0.00004168425,0.000003534282,0.00006336505,0.0006453201,0.000008483576,0.002819531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008714675,"threshold_uncertainty_score":0.0173279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08357468697900058,"score_gpt":0.3458888599221028,"score_spread":0.2623141729431022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}