{"id":"W2170797489","doi":"10.1186/s40064-015-1283-1","title":"A pressure-reversible cellular mechanism of general anesthetics capable of altering a possible mechanism for consciousness","year":2015,"lang":"en","type":"article","venue":"SpringerPlus","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; Health Sciences Centre","funders":"","keywords":"Biophysics; Membrane; Postsynaptic potential; Endocytosis; Exocytosis; Chemistry; Cell membrane; Cell biology; Receptor; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005273806,0.0001921419,0.0003799689,0.0002469351,0.0001390634,0.00003046951,0.0007128657,0.00008981497,0.00002248349],"category_scores_gemma":[0.0003918682,0.0001883884,0.0001158993,0.0004481665,0.0003064439,0.0001987789,0.0002860378,0.0001751253,0.00001132214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002782518,"about_ca_system_score_gemma":0.0002907727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000858565,"about_ca_topic_score_gemma":0.000003142977,"domain_scores_codex":[0.9977955,0.0001517515,0.000368486,0.0005502859,0.0005537813,0.0005802469],"domain_scores_gemma":[0.998745,0.0001523835,0.0002176291,0.0004122661,0.0002451994,0.0002275153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001401092,0.0001254989,0.00006438227,0.0001306095,0.000005961703,0.00004536242,0.0002388589,0.0003753458,0.9643675,0.03438459,0.00008330656,0.00003847529],"study_design_scores_gemma":[0.001157776,0.0005525088,0.000004288591,0.00002035466,0.00003681099,0.00004117513,0.00004032931,0.01986936,0.9711267,0.0065424,0.0004455087,0.000162823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935114,0.00005607725,0.004154755,0.0001310587,0.0008072164,0.0007361672,0.00004153054,0.00005641244,0.0005054236],"genre_scores_gemma":[0.9967644,0.00003475623,0.0007043051,0.0002246716,0.00005607012,0.00005259666,3.765802e-7,0.00003604663,0.002126771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02784219,"threshold_uncertainty_score":0.7682254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0666982750937107,"score_gpt":0.3181180310428127,"score_spread":0.251419755949102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}