{"id":"W2170822335","doi":"10.1111/cbdd.12268","title":"Novel Central Nervous System Drug Delivery Systems","year":2013,"lang":"en","type":"review","venue":"Chemical Biology & Drug Design","topic":"Vagus Nerve Stimulation Research","field":"Neuroscience","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Health Authority","funders":"","keywords":"Drug delivery; Central nervous system; Medicine; Drug; Targeted drug delivery; Blood–brain barrier; Pharmacology; Neuroscience; Biology; Internal medicine; Nanotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000781698,0.000919555,0.002501426,0.0003275204,0.0002163898,0.0001914241,0.001996024,0.0009303968,0.0001064581],"category_scores_gemma":[0.0009037457,0.0006938208,0.0006836593,0.0007265185,0.0005816831,0.0001362489,0.0005252784,0.001351622,0.002545242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007812814,"about_ca_system_score_gemma":0.0006115435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001478154,"about_ca_topic_score_gemma":3.337456e-7,"domain_scores_codex":[0.9927318,0.001914444,0.001371775,0.001779889,0.0004865553,0.001715519],"domain_scores_gemma":[0.9935064,0.0040247,0.0006278115,0.001061539,0.0001679334,0.0006116129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007434883,0.0005535634,0.000009779773,0.0444593,0.000367736,0.0002482574,0.0001460967,0.0002184953,0.2768272,0.005881605,0.04961132,0.6216024],"study_design_scores_gemma":[0.0008048321,0.00006005359,7.352729e-7,0.008091929,0.0005058357,0.000764394,0.00004332285,0.005990077,0.0196949,0.00003995212,0.9621205,0.001883415],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001997448,0.9903436,0.002607659,0.00004620973,0.00151754,0.003723138,0.0002439935,0.0005136594,0.0008044799],"genre_scores_gemma":[0.006252092,0.9882071,0.0007482956,0.000106645,0.001022793,0.001206591,0.0002144265,0.0002141159,0.002027914],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9125092,"threshold_uncertainty_score":0.9995513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1441037085771527,"score_gpt":0.3462729353886773,"score_spread":0.2021692268115245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}