{"id":"W2170849801","doi":"10.1073/pnas.1319900111","title":"Small cationic antimicrobial peptides delocalize peripheral membrane proteins","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":340,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"European Regional Development Fund; European Commission","keywords":"Antimicrobial peptides; Antimicrobial; Peptide; Bacteria; Mode of action; Biology; Antibiotics; Peripheral membrane protein; Membrane; Membrane protein; Chemistry; Microbiology; Biochemistry; Integral membrane protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008042929,0.0001205614,0.0002090681,0.0001004566,0.0003729789,0.00002480889,0.0006738292,0.0001378029,0.00004954092],"category_scores_gemma":[0.0002841685,0.00008212759,0.0001119586,0.000303186,0.001690907,0.0002714353,0.0001363335,0.0001967525,0.00000856086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000249536,"about_ca_system_score_gemma":0.00004143802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004666141,"about_ca_topic_score_gemma":7.820136e-7,"domain_scores_codex":[0.9990733,0.00001817934,0.0003173621,0.0002375506,0.0001401409,0.0002134421],"domain_scores_gemma":[0.9992928,0.00008511222,0.0003879457,0.00001035352,0.0002119287,0.0000118622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002303477,0.00004824105,0.001257497,0.0000603277,0.00002313666,1.036162e-9,0.0001642176,0.00007547508,0.9612606,0.03543757,0.001327289,0.0003226681],"study_design_scores_gemma":[0.000290678,0.00006186498,0.008757633,0.0001101765,0.00001511311,0.00002307987,0.0001061583,0.00008876232,0.9839447,0.004847866,0.001642385,0.0001115679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901651,0.00007158492,0.00001376595,0.002417584,0.00005127056,0.0002140237,0.0000190221,0.00002132869,0.007026286],"genre_scores_gemma":[0.996817,0.00002137928,0.001317995,0.0004570967,0.00006047038,0.000007696906,7.077315e-7,0.000005635584,0.001312043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0305897,"threshold_uncertainty_score":0.6230218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03018084020034893,"score_gpt":0.2548116502480862,"score_spread":0.2246308100477373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}