{"id":"W2170918198","doi":"10.1242/jcs.03007","title":"Sphingomyelin-enriched microdomains define the efficiency of native Ca2+-triggered membrane fusion","year":2006,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Lipid microdomain; Sphingomyelin; Biology; Vesicle; Cell biology; Lipid bilayer fusion; Ceramide; Vesicle fusion; Membrane curvature; Raft; Lipid raft; Membrane; Biophysics; Biochemistry; Chemistry; Signal transduction; Synaptic vesicle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008701695,0.0001122215,0.0001704122,0.00009459308,0.000161726,0.00002593644,0.0005910736,0.00006003068,0.0000174634],"category_scores_gemma":[0.0001098916,0.00006499742,0.0001280809,0.0004132615,0.0004584728,0.00001267142,0.00009445299,0.0001346281,0.000001141104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001966605,"about_ca_system_score_gemma":0.0003179765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003057086,"about_ca_topic_score_gemma":0.00001535393,"domain_scores_codex":[0.9987052,0.00004276086,0.0003931347,0.0001774299,0.0004592114,0.0002222664],"domain_scores_gemma":[0.9988037,0.00002589004,0.0004685322,0.0002233614,0.0004154829,0.00006302122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003401597,0.00007608601,0.0002076646,0.000008179581,0.000002908877,0.000003727539,0.000087906,0.00008258184,0.9989984,0.00002628811,0.0001687992,0.0003034272],"study_design_scores_gemma":[0.0005118292,0.000245247,0.002040507,0.000008721471,0.00002981503,0.00007630821,0.00009784198,0.00001929917,0.9946793,0.00002390136,0.002183252,0.00008395179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971873,0.0003707757,0.000350609,0.0001474642,0.0003739069,0.00009102028,0.000003931752,0.000001681756,0.00147338],"genre_scores_gemma":[0.9984662,0.00009023901,0.0006998503,0.0000634459,0.0004119009,5.536223e-7,0.000002195264,0.000006223952,0.0002594033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004319089,"threshold_uncertainty_score":0.2650518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005222038615267616,"score_gpt":0.2299947576265738,"score_spread":0.2247727190113062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}