{"id":"W2171050441","doi":"10.1095/biolreprod.114.127761","title":"Novel Targets for the Transcription Factors MEF2 in MA-10 Leydig Cells1","year":2015,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Mef2; Biology; Transcription factor; Gene knockdown; Enhancer; Cell biology; MEF2C; Leydig cell; Gene; Genetics; Endocrinology; Luteinizing hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001772969,0.0005316004,0.0003628593,0.0003541022,0.000310577,0.0004772389,0.0002837924,0.0003849165,0.003849071],"category_scores_gemma":[0.0001811854,0.0002145886,0.0005067557,0.0001988569,0.0002527924,0.0001818767,0.0002837646,0.000588843,0.001324525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004350666,"about_ca_system_score_gemma":0.0002447337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009252155,"about_ca_topic_score_gemma":0.001468334,"domain_scores_codex":[0.9997907,0.00002082811,0.000009901362,0.00006038218,0.00007912367,0.00003902338],"domain_scores_gemma":[0.9998547,0.00002455203,0.00003565622,0.00001274802,0.00002789006,0.00004447164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001074341,0.00002225632,0.0006705348,0.00007479058,0.000009776354,0.000161184,0.00001859811,0.00005319732,0.9969991,0.000140992,0.0002459835,0.001496142],"study_design_scores_gemma":[0.00003857732,0.0003427852,0.04057451,0.00003645961,0.00006251239,0.001188598,0.00008892924,0.001305205,0.9331124,0.000153967,0.02307433,0.00002159357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9430605,0.0219449,0.01640965,0.0006966362,0.0005719811,0.00012342,0.005566476,0.000980664,0.01064574],"genre_scores_gemma":[0.9710779,0.002535218,0.005625594,0.0003976637,0.00008234195,0.0001303984,0.004255427,0.0001169395,0.01577848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003849071,"threshold_uncertainty_score":0.01287639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04630336887285586,"score_gpt":0.2908064038304577,"score_spread":0.2445030349576019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}