{"id":"W2171050441","doi":"10.1095/biolreprod.114.127761","title":"Novel Targets for the Transcription Factors MEF2 in MA-10 Leydig Cells1","year":2015,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Mef2; Biology; Transcription factor; Gene knockdown; Enhancer; Cell biology; MEF2C; Leydig cell; Gene; Genetics; Endocrinology; Luteinizing hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003308775,0.0000845479,0.000113064,0.0000258019,0.00003617645,0.000004062234,0.000104795,0.0001286919,0.00001640742],"category_scores_gemma":[0.0001809347,0.00005900787,0.00007073383,0.00004432723,0.0001443169,0.000003924275,0.00001856748,0.00004282802,0.000002157039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007321011,"about_ca_system_score_gemma":0.00003369637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004718607,"about_ca_topic_score_gemma":0.00003686807,"domain_scores_codex":[0.999294,0.00003019841,0.0002279863,0.0002799355,0.00004880378,0.0001190149],"domain_scores_gemma":[0.9995289,0.00001889636,0.0000885284,0.0002120622,0.000121713,0.00002989311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003510817,0.0002535299,0.004915436,0.00003275986,0.00005058968,1.292187e-7,0.0003618177,0.0001542089,0.9689336,0.000569538,0.001824566,0.02255271],"study_design_scores_gemma":[0.0009149647,0.0008936809,0.009776596,0.000004877655,0.00001651558,0.000006241925,0.00122032,0.00004324286,0.7533958,0.0006428313,0.2329567,0.0001282444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907641,0.003149212,0.003953028,0.0008552638,0.0006596404,0.0002507321,0.00002145319,0.000008002731,0.0003386129],"genre_scores_gemma":[0.9965773,0.0002226293,0.000520297,0.00003354009,0.0002698494,0.00002336875,0.0001200643,0.000006324992,0.002226603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2311321,"threshold_uncertainty_score":0.2406271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04630336887285586,"score_gpt":0.2908064038304577,"score_spread":0.2445030349576019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}