{"id":"W2171067659","doi":"10.1096/fj.10-174318","title":"Tetrameric far‐red fluorescent protein as a scaffold to assemble an octavalent peptide nanoprobe for enhanced tumor targeting and intracellular uptake <i>in vivo</i>","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Nanoprobe; In vivo; Fluorophore; Chemistry; Fluorescence; Intracellular; Peptide; In vitro; Biophysics; Preclinical imaging; Molecular probe; Molecular imaging; Molecular biology; Biochemistry; Biology; DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001611025,0.0004038564,0.0001500105,0.0002114135,0.0001159416,0.0001699729,0.0002223572,0.0004444181,0.0006030411],"category_scores_gemma":[0.0001193246,0.0001586981,0.0001905279,0.00009290854,0.0001585018,0.0002730755,0.0002046514,0.0002580148,0.0004065188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000254154,"about_ca_system_score_gemma":0.0001796824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005250858,"about_ca_topic_score_gemma":0.0007967497,"domain_scores_codex":[0.9998968,0.00001645361,0.000007720794,0.00003157472,0.00002440636,0.00002303263],"domain_scores_gemma":[0.9999273,0.00000997907,0.00002361286,0.000007958376,0.00001654505,0.00001464197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008993402,0.000007777516,0.00003639266,0.00002092381,0.00000194942,0.00002406635,0.00001084772,0.0001492139,0.9983965,0.0001287481,0.00004154175,0.001173008],"study_design_scores_gemma":[0.000005051395,0.00006741606,0.000298754,0.000002600017,0.000005123378,0.0001267095,0.000008213858,0.003585538,0.9942416,0.00003060299,0.001623145,0.000005251052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8855987,0.001687224,0.1088753,0.0002149403,0.00005205619,0.0001003956,0.0002154186,0.0005910466,0.00266492],"genre_scores_gemma":[0.902669,0.0006633205,0.09255365,0.0001619853,0.00001392127,0.0000987629,0.0003122014,0.00008401787,0.003443282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006030411,"threshold_uncertainty_score":0.002017379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01687207111145134,"score_gpt":0.2633946621208409,"score_spread":0.2465225910093896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}