{"id":"W2171070862","doi":"10.1111/j.1463-1326.2005.00524.x","title":"Glucose control with insulin results in reduction of NF‐κB‐binding activity in mononuclear blood cells of patients with recently manifested type 1 diabetes","year":2005,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Deutsche Diabetes Gesellschaft; Heart and Stroke Foundation of Canada","keywords":"Electrophoretic mobility shift assay; Western blot; Internal medicine; Endocrinology; Transcription factor; Peripheral blood mononuclear cell; Insulin; P50; NF-κB; Cytoplasm; Diabetes mellitus; Oxidative stress; Glycation; Biology; Molecular biology; Chemistry; Medicine; Biochemistry; In vitro; Gene; Inflammation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001524689,0.000323608,0.0003502839,0.0002670259,0.0003082966,0.0003234899,0.0001145119,0.0003057154,0.00112401],"category_scores_gemma":[0.0005478517,0.0001572832,0.0001860799,0.000274914,0.0001451199,0.0001266886,0.0001176236,0.000344366,0.0001825502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001640818,"about_ca_system_score_gemma":0.00006834605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003810266,"about_ca_topic_score_gemma":0.0004004217,"domain_scores_codex":[0.9998649,0.00002952118,0.00001707418,0.00004875015,0.00001907565,0.00002071806],"domain_scores_gemma":[0.9997442,0.00004365056,0.0001063664,0.00001525465,0.00002321978,0.00006727293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005652728,0.0004928451,0.9085651,0.0001224402,0.0001520082,0.002619657,0.0004363437,0.0001054897,0.06595568,0.00002780697,0.0002665261,0.01560338],"study_design_scores_gemma":[0.00009451927,0.001626301,0.9891038,0.00001584718,0.0000983131,0.005368486,0.0002565177,0.0001948767,0.002681712,0.00002598995,0.0005260828,0.000007478177],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992546,0.0004669933,0.00009667692,0.00001812507,0.000006981787,0.000002924861,0.00003419719,0.000004497604,0.0001148779],"genre_scores_gemma":[0.9994815,0.0001571379,0.0001054963,0.00002969214,0.00001335064,0.00000481845,0.00009175466,0.000001992126,0.0001142785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00112401,"threshold_uncertainty_score":0.003760219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005343959516033108,"score_gpt":0.2151385438856048,"score_spread":0.2097945843695717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}