{"id":"W2171070862","doi":"10.1111/j.1463-1326.2005.00524.x","title":"Glucose control with insulin results in reduction of NF‐κB‐binding activity in mononuclear blood cells of patients with recently manifested type 1 diabetes","year":2005,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Deutsche Diabetes Gesellschaft; Heart and Stroke Foundation of Canada","keywords":"Electrophoretic mobility shift assay; Western blot; Internal medicine; Endocrinology; Transcription factor; Peripheral blood mononuclear cell; Insulin; P50; NF-κB; Cytoplasm; Diabetes mellitus; Oxidative stress; Glycation; Biology; Molecular biology; Chemistry; Medicine; Biochemistry; In vitro; Gene; Inflammation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003076715,0.0001332728,0.0002753199,0.0001390439,0.00002861552,0.000007066097,0.00009582012,0.00009703287,0.000003418059],"category_scores_gemma":[0.000111492,0.0001144034,0.00001812698,0.0003112192,0.0001088108,0.00003316963,0.00004350029,0.0001382268,8.50051e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000103802,"about_ca_system_score_gemma":0.00004341554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001869427,"about_ca_topic_score_gemma":0.00003202838,"domain_scores_codex":[0.9988967,0.0001369573,0.0002326075,0.0003278388,0.0001610143,0.0002448462],"domain_scores_gemma":[0.9993068,0.00002376318,0.0001772781,0.000244018,0.0001934296,0.0000547321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009999254,0.000713183,0.119425,0.00007215323,0.00006133461,3.573725e-7,0.0001291553,0.0006593383,0.8702432,0.00000861471,0.000005293738,0.007682508],"study_design_scores_gemma":[0.002967269,0.0002261085,0.314333,0.00003309041,0.0000231843,9.727088e-8,0.00001546572,0.00003100954,0.6818589,0.000006308728,0.0004088854,0.00009663107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998563,0.0008668718,0.000005061144,0.00005577276,0.00003359375,0.0003567011,0.0000744826,0.000004554432,0.00003999639],"genre_scores_gemma":[0.9982857,0.0006475822,0.0008813285,0.0000149741,0.00004086683,0.000008560728,0.00007133333,0.00001551335,0.00003411652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1949081,"threshold_uncertainty_score":0.4665236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005343959516033108,"score_gpt":0.2151385438856048,"score_spread":0.2097945843695717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}