{"id":"W2171077730","doi":"10.1161/hc4201.097134","title":"Ionic Remodeling of Cardiac Purkinje Cells by Congestive Heart Failure","year":2001,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Heart Institute","funders":"Heart and Stroke Foundation of Canada; AstraZeneca; Pfizer Pharmaceuticals; Pfizer","keywords":"Heart failure; Medicine; Internal medicine; Repolarization; Cardiology; Purkinje fibers; Calcium; Cardiac transient outward potassium current; Endocrinology; Electrophysiology; Patch clamp","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001894298,0.0002932596,0.0002620124,0.0001756822,0.00009979576,0.000145136,0.0001614083,0.0002308575,0.0006756326],"category_scores_gemma":[0.0005396841,0.0001117362,0.0001033415,0.00008801667,0.0004231937,0.0002150511,0.0001875165,0.0002441579,0.0001124891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001522589,"about_ca_system_score_gemma":0.0000901774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000204222,"about_ca_topic_score_gemma":0.0002813138,"domain_scores_codex":[0.9999069,0.00002067005,0.00001080973,0.00001775034,0.00002701596,0.00001679184],"domain_scores_gemma":[0.9997336,0.00005882277,0.0001003811,0.00001921519,0.00002088827,0.00006714139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001689711,0.00007144883,0.04717211,0.0001046482,0.00003510935,0.002807429,0.000133832,0.000316814,0.9400107,0.0001083671,0.0001886966,0.007361101],"study_design_scores_gemma":[0.0002450434,0.002501333,0.8977087,0.00002709704,0.00007706076,0.01410198,0.0002078122,0.002059068,0.08158891,0.000347215,0.001113906,0.00002182489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990717,0.000299479,0.0003703861,0.00001852752,0.000005150802,0.000005502114,0.00002437341,0.00001301517,0.0001917203],"genre_scores_gemma":[0.9995587,0.0001276557,0.0001614852,0.00002011588,0.00001323974,0.000005960886,0.00005350731,0.000003347755,0.00005595445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006756326,"threshold_uncertainty_score":0.002260149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009286935958369486,"score_gpt":0.2408602235339057,"score_spread":0.2315732875755362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}