{"id":"W2171206539","doi":"10.1016/j.virol.2009.12.008","title":"Human hepatoma cells transmit surface bound HIV-1 to CD4+ T cells through an ICAM-1/LFA-1-dependent mechanism","year":2009,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Canada Research Chairs","keywords":"Biology; Virus; Human immunodeficiency virus (HIV); Virology; Hepatocyte; ICAM-1; Cell; Cell biology; In vitro; Cell adhesion molecule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000281222,0.0003874942,0.0005660131,0.0001216056,0.0004564699,0.00003607436,0.0005467287,0.0005362496,0.002849083],"category_scores_gemma":[0.000006730598,0.0003466028,0.0001505457,0.0001536762,0.000200796,0.0001749276,0.00007774035,0.0004956916,0.01359938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009899132,"about_ca_system_score_gemma":0.00007473788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003541945,"about_ca_topic_score_gemma":0.0003282555,"domain_scores_codex":[0.9969446,0.0005601432,0.0004013258,0.00081581,0.00009885936,0.001179273],"domain_scores_gemma":[0.9989026,0.00007282902,0.00007801666,0.0007241197,0.00005695667,0.0001654683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002642165,0.0008679422,0.00007230803,0.000006184392,0.0001668967,0.000275783,0.0009532025,0.00004102823,0.9864526,0.004702575,0.005214092,0.0009831663],"study_design_scores_gemma":[0.003382961,0.005782423,0.003018385,0.000008317881,0.00008536218,0.0001462648,0.0001356915,0.00000601887,0.9130086,0.004577413,0.06937564,0.0004729399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916076,0.0005799817,0.001268827,0.001954192,0.0004432527,0.000715016,0.0003042839,0.0001837583,0.002943074],"genre_scores_gemma":[0.9907535,0.0001045766,0.0005473787,0.001747805,0.00005397784,0.00003155947,0.0002428185,0.00003482224,0.00648362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07344402,"threshold_uncertainty_score":0.9998986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0171309641111372,"score_gpt":0.2760617672747946,"score_spread":0.2589308031636575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}