{"id":"W2171247775","doi":"10.1161/01.cir.0000124229.40424.80","title":"Taurine Supplementation Reduces Oxidative Stress and Improves Cardiovascular Function in an Iron-Overload Murine Model","year":2004,"lang":"en","type":"article","venue":"Circulation","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":223,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Heart and Stroke Foundation of Canada","keywords":"Taurine; Oxidative stress; Medicine; Internal medicine; Endocrinology; Lipid peroxidation; Diastole; Cardiac function curve; Glutathione; Heart failure; Blood pressure; Amino acid; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002240442,0.0007685258,0.0006991526,0.0007808365,0.0002994484,0.0002639136,0.0004713702,0.0008207549,0.001043968],"category_scores_gemma":[0.0001497403,0.0001873219,0.0003700492,0.0001748493,0.0003298001,0.0003215126,0.0001873941,0.0008887867,0.0002299329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002346749,"about_ca_system_score_gemma":0.0002435141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003599186,"about_ca_topic_score_gemma":0.000728756,"domain_scores_codex":[0.999911,0.00001629805,0.00001093718,0.00001971459,0.00001997843,0.00002208232],"domain_scores_gemma":[0.9997497,0.00001320711,0.00009060056,0.00002283404,0.00003344758,0.00009017524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002967897,0.001009174,0.0005130995,0.0001699425,0.00004016454,0.0001656747,0.00003788881,0.0001239729,0.9894854,0.00006890948,0.0002090904,0.005208669],"study_design_scores_gemma":[0.001039841,0.02398859,0.01250845,0.0001244535,0.0004268533,0.0008390296,0.00009109986,0.00262485,0.9526449,0.0002959443,0.005378559,0.00003741213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916388,0.00410935,0.002284407,0.0003430412,0.00009353505,0.00007513037,0.0003335285,0.0002233914,0.0008987183],"genre_scores_gemma":[0.9869393,0.00322904,0.004962097,0.0002202664,0.00007020895,0.0001767126,0.0007425878,0.00004344423,0.003616236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001043968,"threshold_uncertainty_score":0.003492475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01117413097649155,"score_gpt":0.2454254016495412,"score_spread":0.2342512706730497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}