{"id":"W2171279452","doi":"10.1093/molbev/msq108","title":"Low-Complexity Regions in Plasmodium falciparum: Missing Links in the Evolution of an Extreme Genome","year":2010,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Malaria Research and Control","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Plasmodium falciparum; Evolutionary biology; Genome; Malaria; Genetics; Population; Molecular evolution; Selection (genetic algorithm); Negative selection; Gene; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006296281,0.00008628071,0.0001740026,0.0001942839,0.00006356283,0.00000595298,0.0001003161,0.0002998434,0.00001511346],"category_scores_gemma":[0.0001880946,0.000064739,0.00003860795,0.0001975029,0.0002795125,0.00004552862,0.00002630485,0.0005973694,0.000002280979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006159627,"about_ca_system_score_gemma":0.0001213248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008861166,"about_ca_topic_score_gemma":0.001502693,"domain_scores_codex":[0.9989863,0.0002571022,0.000197749,0.00021124,0.00009120568,0.0002564063],"domain_scores_gemma":[0.999552,0.00003427923,0.00004735754,0.0002494063,0.00004913006,0.00006789048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003945468,0.0002198273,0.02064155,0.00003093699,0.000009832071,0.00002975813,0.000168077,0.00001038192,0.9057112,0.07198592,0.000006506164,0.0007914414],"study_design_scores_gemma":[0.001863761,0.0003937566,0.945612,0.00003002631,0.00002007301,0.00007585242,0.0002080021,0.00686969,0.001403083,0.04332893,0.0001039665,0.00009086268],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775643,0.0004339631,0.01621021,0.004939445,0.00004560224,0.0003325166,0.000005706449,0.000009769361,0.0004584488],"genre_scores_gemma":[0.9991531,0.000009097647,0.0005797741,0.0001250544,0.00004615829,0.0000220457,0.00004795387,0.00000482268,0.00001195966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9249704,"threshold_uncertainty_score":0.263998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02793015595149444,"score_gpt":0.3002307818309733,"score_spread":0.2723006258794788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}