{"id":"W2171293586","doi":"10.1016/j.biomaterials.2010.02.076","title":"The effects of co-culture with fibroblasts and angiogenic growth factors on microvascular maturation and multi-cellular lumen formation in HUVEC-oriented polymer fibre constructs","year":2010,"lang":"en","type":"article","venue":"Biomaterials","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health and Social Services Centre University Institute of Geriatrics of Sherbrooke; Université de Sherbrooke","funders":"","keywords":"Microvessel; Fibrin; Umbilical vein; Angiogenesis; Human umbilical vein endothelial cell; Basic fibroblast growth factor; Materials science; Lumen (anatomy); Biomedical engineering; Cell biology; Neovascularization; In vitro; Biophysics; Growth factor; Chemistry; Immunology; Biology; Cancer research; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008097809,0.0001346994,0.0001353006,0.00003054664,0.00007967537,0.00003541296,0.00005267968,0.0001453351,0.000002320373],"category_scores_gemma":[0.00002795789,0.00008172027,0.00003541988,0.00004639988,0.0001294214,0.00001067899,0.00002788203,0.00001205608,4.442783e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004925677,"about_ca_system_score_gemma":0.00001303122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002955373,"about_ca_topic_score_gemma":0.00002805832,"domain_scores_codex":[0.9994021,0.0000535298,0.0001634836,0.0001797401,0.00007317894,0.0001279568],"domain_scores_gemma":[0.9996485,0.00001553293,0.0001122492,0.0001438906,0.00004459006,0.00003529715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001482845,0.00001598094,0.002668648,0.0000895116,0.00004586102,0.000001014192,0.0001128405,8.966126e-8,0.9966289,0.0000317928,0.00008926327,0.0001678386],"study_design_scores_gemma":[0.0008376511,0.0002418378,0.01108054,0.00004540239,0.00001899114,0.0000133295,0.00006807081,0.000004849917,0.9872311,0.000002661269,0.0003465102,0.0001090274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982892,0.001171774,0.00006380164,0.00001652475,0.0001281728,0.0002891514,0.00002993233,0.000005139292,0.000006261302],"genre_scores_gemma":[0.9993222,0.0002266447,0.0001918817,0.00001759098,0.00004743287,0.00001584207,0.0001415505,0.00001204787,0.0000248441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009397743,"threshold_uncertainty_score":0.3332456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003422803378268538,"score_gpt":0.2107459798977945,"score_spread":0.2073231765195259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}