{"id":"W2171296947","doi":"10.4049/jimmunol.1203518","title":"<i>Leishmania</i>-Infected MHC Class IIhigh Dendritic Cells Polarize CD4+ T Cells toward a Nonprotective T-bet+ IFN-γ+ IL-10+ Phenotype","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Biology; Immunology; Immune system; Bystander effect; Population; Adoptive cell transfer; MHC class II; T cell; Major histocompatibility complex; Interleukin 4; Dendritic cell; Phenotype; Leishmania major; Leishmania; Medicine; Parasite hosting; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001215189,0.0004359477,0.001156069,0.0004389651,0.0003203955,0.00007647962,0.0008333018,0.000313476,0.001652919],"category_scores_gemma":[0.0008296972,0.0002792553,0.0003568921,0.0005662409,0.0008224854,0.0003616472,0.000422184,0.002066848,0.001590503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004185832,"about_ca_system_score_gemma":0.0004317949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009164402,"about_ca_topic_score_gemma":0.00003709115,"domain_scores_codex":[0.99594,0.0009499484,0.001039832,0.0002968057,0.0007606519,0.001012811],"domain_scores_gemma":[0.9954943,0.0008605834,0.0007160045,0.0007372203,0.00195581,0.0002360705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001577891,0.0004579378,0.0002434106,0.0000846976,0.001868886,0.0001808932,0.002142955,0.00001222583,0.975262,0.0000901973,0.014332,0.003746914],"study_design_scores_gemma":[0.01450978,0.01498599,0.1518315,0.0007382462,0.001710711,0.004220125,0.007483946,0.0002115771,0.7650129,0.002833635,0.03536901,0.001092581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773484,0.004196675,0.0005204671,0.011555,0.001046876,0.001339162,0.00001507614,0.00007494129,0.003903388],"genre_scores_gemma":[0.9935558,0.001883368,0.000677914,0.0008732302,0.000487752,0.00003523297,0.000002424438,0.00007903825,0.00240527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2102491,"threshold_uncertainty_score":0.999966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01812909105293248,"score_gpt":0.2606635068187299,"score_spread":0.2425344157657974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}