{"id":"W2171331783","doi":"10.1073/pnas.1421450112","title":"Oligoribonuclease is a central feature of cyclic diguanylate signaling in <i>Pseudomonas aeruginosa</i>","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Calgary","funders":"Canadian Institutes of Health Research; Israel Science Foundation; National Institute of Allergy and Infectious Diseases; Federation of European Microbiological Societies; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Pseudomonas aeruginosa; Intracellular; Nuclease; Biology; Extracellular; Phosphodiesterase; Biochemistry; Microbiology; Enzyme; Chemistry; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001298283,0.0004031019,0.0002396,0.0001502893,0.0001428637,0.0003150901,0.0001348131,0.0002876236,0.0004855061],"category_scores_gemma":[0.0001687692,0.0001297947,0.0002202627,0.0001159642,0.0002222184,0.0002059915,0.000162383,0.000317254,0.0003321416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002299965,"about_ca_system_score_gemma":0.0001672652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005290703,"about_ca_topic_score_gemma":0.0006049157,"domain_scores_codex":[0.9998232,0.00001874217,0.000016585,0.00006245555,0.00005334123,0.00002573214],"domain_scores_gemma":[0.9998462,0.00002732984,0.0000615808,0.00001699423,0.00002137651,0.00002646528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001012153,0.000002263381,0.0001718378,0.00001477995,0.000001058772,0.00002494196,0.000003482884,0.000007376662,0.9990287,0.0000159188,0.000005283308,0.000714251],"study_design_scores_gemma":[0.000001095405,0.00005853407,0.006356653,0.000002640742,0.000004683174,0.0003520541,0.0000117023,0.0001777378,0.9919564,0.00003109047,0.001044489,0.000002873683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978508,0.004704717,0.01375962,0.0001910767,0.00004228109,0.0000473097,0.000621394,0.0002428787,0.00188282],"genre_scores_gemma":[0.9859182,0.001272695,0.008921964,0.0001471874,0.00001751284,0.00003505429,0.001036212,0.0000411409,0.002610097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005290703,"threshold_uncertainty_score":0.001668751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02747558185055426,"score_gpt":0.274165430406954,"score_spread":0.2466898485563997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}