{"id":"W2171406189","doi":"10.1152/ajpheart.00230.2004","title":"Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP","year":2004,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Matrix metalloproteinase; Phosphatidylinositol; Kinase; Cell biology; Chemistry; Expression (computer science); Biology; Biochemistry; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001893078,0.0004838029,0.0003395388,0.0003265254,0.0001859096,0.0004235283,0.0001269378,0.0002674079,0.001423133],"category_scores_gemma":[0.0001499841,0.0002316533,0.0004090187,0.0002121627,0.0002061214,0.0002040439,0.0001771982,0.0007348347,0.0005489078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002768972,"about_ca_system_score_gemma":0.0001796312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002598213,"about_ca_topic_score_gemma":0.0005391188,"domain_scores_codex":[0.9998096,0.00003080956,0.00001807537,0.00002981381,0.00006802662,0.00004370411],"domain_scores_gemma":[0.9998925,0.00001532095,0.00003726602,0.00001384875,0.00001529538,0.00002577096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001160885,0.00002665833,0.0001991958,0.00005409873,0.000006173007,0.00005771762,0.00001108871,0.00001414845,0.998238,0.00002597857,0.00002523266,0.001225588],"study_design_scores_gemma":[0.00002210569,0.0004275965,0.01421516,0.000007214655,0.00002242915,0.0005742587,0.00002273086,0.0008358786,0.9817648,0.00006235966,0.002040516,0.00000486417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842131,0.006549054,0.006514041,0.0001649445,0.00005841711,0.00008378349,0.0004833943,0.000144985,0.001788245],"genre_scores_gemma":[0.9856916,0.004537522,0.004332881,0.00005113339,0.00005032998,0.00009449443,0.0009618214,0.00001864724,0.00426166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001423133,"threshold_uncertainty_score":0.004760802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005124438042303183,"score_gpt":0.232564669233758,"score_spread":0.2274402311914548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}