{"id":"W2171411430","doi":"10.4137/cmo.s615","title":"Multiple Myeloma Includes Phenotypically Defined Subsets of Clonotypic CD20+ B Cells that Persist during Treatment with Rituximab","year":2008,"lang":"en","type":"article","venue":"Clinical medicine Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"CD20; Rituximab; CD19; B cell; Multiple myeloma; Immunology; Plasma cell; clone (Java method); Medicine; Antibody; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001042993,0.0001607499,0.0002001388,0.0002605123,0.0001719733,0.0002252711,0.00008550201,0.0001547446,0.0008873165],"category_scores_gemma":[0.0001445131,0.00008608196,0.0001118432,0.0001963151,0.00009038979,0.0001256161,0.0001307486,0.0001675011,0.0001868649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000169588,"about_ca_system_score_gemma":0.0001193149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000635597,"about_ca_topic_score_gemma":0.001128207,"domain_scores_codex":[0.9999123,0.00001307244,0.000006786523,0.00001890703,0.00002907929,0.00001985446],"domain_scores_gemma":[0.9999114,0.00001580859,0.00002667746,0.000008984605,0.00001538866,0.00002168159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004495172,0.00004129486,0.03061106,0.00005355095,0.0000240745,0.0003476602,0.00009322251,0.000117888,0.9427734,0.0001564383,0.0001240023,0.02520793],"study_design_scores_gemma":[0.00005883255,0.001456695,0.5781206,0.00002020722,0.0001140691,0.01248699,0.0001793909,0.0009692418,0.3983152,0.000287949,0.007976504,0.00001431254],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996466,0.001676046,0.0008531519,0.0000246228,0.000002289124,0.000009760296,0.0001024801,0.00004043667,0.0008252075],"genre_scores_gemma":[0.9981365,0.0003704714,0.0006644993,0.00002600409,0.000005628029,0.00001170204,0.000250947,0.000007177561,0.0005270165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008873165,"threshold_uncertainty_score":0.002968311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1118333981794362,"score_gpt":0.3866858537468932,"score_spread":0.274852455567457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}