{"id":"W2171520460","doi":"10.1051/medsci/2006223301","title":"Activité dominante négative des protéines p53 mutées","year":2006,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Sherbrooke","funders":"","keywords":"Philosophy; Molecular biology; P53 protein; Humanities; Biology; Genetics; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["metaepi_narrow","sts"],"category_scores_codex":[0.002241123,0.001567397,0.003380024,0.0009567043,0.001399869,0.000281956,0.001269841,0.0008511668,0.0009017661],"category_scores_gemma":[0.001427326,0.001180154,0.001173197,0.003916105,0.007036011,0.0005289566,0.0004044262,0.001280483,0.001283988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001010339,"about_ca_system_score_gemma":0.003031219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001713153,"about_ca_topic_score_gemma":0.0006383864,"domain_scores_codex":[0.9916303,0.0007734338,0.001681399,0.002182452,0.00169495,0.00203748],"domain_scores_gemma":[0.9958959,0.001136741,0.001248185,0.0008921786,0.0003729556,0.0004540781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009402426,0.001130254,0.002590505,0.01745096,0.0006836312,0.0006439154,0.0005219411,0.0001850516,0.001640768,0.004091148,0.006169453,0.9647983],"study_design_scores_gemma":[0.00281587,0.00278958,0.001805572,0.07120179,0.003360184,0.001355255,0.0004716087,0.0003637625,0.003340881,0.001959972,0.9087287,0.001806869],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006113545,0.9453081,0.001033283,0.0004588616,0.003311238,0.004184971,0.0001823073,0.0001813554,0.03922631],"genre_scores_gemma":[0.003355464,0.9773431,0.004548622,0.0001657238,0.002952635,0.0008091207,0.00009296288,0.0001915471,0.01054081],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9629915,"threshold_uncertainty_score":0.9999002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07159985518986822,"score_gpt":0.3578444989389012,"score_spread":0.286244643749033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}