{"id":"W2171613528","doi":"10.1038/nature13393","title":"Targeting transcription regulation in cancer with a covalent CDK7 inhibitor","year":2014,"lang":"en","type":"article","venue":"Nature","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":900,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institute of Neurological Disorders and Stroke; National Human Genome Research Institute","keywords":"Cyclin-dependent kinase 7; Cyclin-dependent kinase; Kinase; Transcription factor; Transcription (linguistics); Cancer research; Biology; Chemistry; Cell biology; Biochemistry; Cell; Cell cycle; Protein kinase A; Cyclin-dependent kinase 2; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004797204971728208,"score_gpt":0.2364676590853878,"score_spread":0.2316704541136596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}