{"id":"W2171651467","doi":"10.4049/jimmunol.1300435","title":"Simultaneous TCR and CD244 Signals Induce Dynamic Downmodulation of CD244 on Human Antiviral T Cells","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases","keywords":"T-cell receptor; Internalization; Biology; T cell; CD8; Cell biology; Molecular biology; Antigen; Immunology; Receptor; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006397033,0.0002490183,0.0001359623,0.0000985689,0.00009381333,0.000248383,0.0001025697,0.0001931605,0.001695918],"category_scores_gemma":[0.000110593,0.00009822211,0.0001729986,0.00008625345,0.00007903065,0.0001356089,0.0001983116,0.0003803513,0.0004423431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001496133,"about_ca_system_score_gemma":0.00007158675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001091993,"about_ca_topic_score_gemma":0.0001661111,"domain_scores_codex":[0.9998502,0.00002449041,0.00001114972,0.00002986283,0.00002854626,0.00005572539],"domain_scores_gemma":[0.9999454,0.00001774023,0.000008778182,0.00001150361,0.000005662985,0.00001075009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009737648,0.00001567625,0.0001078273,0.00001402448,0.000002610604,0.0000435453,0.00000841486,0.00003302062,0.9986537,0.00003223003,0.00001696577,0.0009746414],"study_design_scores_gemma":[0.00001384862,0.0002953252,0.003500471,0.000005357591,0.00001176892,0.0003673191,0.00002021876,0.0006138797,0.993905,0.00003088295,0.00123309,0.000002853937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980947,0.0004295157,0.0005463007,0.00001542545,0.000009383524,0.000008679352,0.00006219198,0.00001696278,0.0008168689],"genre_scores_gemma":[0.9980705,0.0002326233,0.0004937216,0.00002677523,0.000007796317,0.00001556432,0.0001609455,0.00000642021,0.0009855967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001695918,"threshold_uncertainty_score":0.005673468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01097761532593689,"score_gpt":0.2455986152577656,"score_spread":0.2346209999318287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}