{"id":"W2171710359","doi":"10.1086/379664","title":"Enzymatic Degradation of Prion Protein in Brain Stem from Infected Cattle and Sheep","year":2003,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nutrasource","funders":"National Chung-Hsing University","keywords":"Bovine spongiform encephalopathy; Scrapie; Proteinase K; Proteases; Pepsin; Enzyme; Transmissible spongiform encephalopathy; Proteolytic enzymes; Trypsin; Microbiology; Biology; Biochemistry; Virology; Prion protein; Chemistry; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002645507,0.00008696959,0.0001392276,0.00006082069,0.00004137208,0.00001430723,0.00007643749,0.00004561499,0.00002033522],"category_scores_gemma":[0.0004329338,0.00006273188,0.00005944682,0.00009744478,0.0000465755,0.00001119591,0.00002520099,0.0000691388,5.532828e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001728205,"about_ca_system_score_gemma":0.0001020392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005218485,"about_ca_topic_score_gemma":0.00004487174,"domain_scores_codex":[0.9991421,0.0003012466,0.0002814702,0.00007440052,0.0001093583,0.00009138833],"domain_scores_gemma":[0.9993704,0.00007146088,0.0002803416,0.00013197,0.00008155174,0.00006429129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004281606,0.000409902,0.2719903,0.0001323907,0.0001771628,0.00000521427,0.000222148,0.0005827208,0.7023215,0.0001938229,0.0002990022,0.0232376],"study_design_scores_gemma":[0.005631105,0.001771918,0.4082622,0.0006678999,0.00034915,0.0001332867,0.000635705,0.0001379666,0.5747972,0.005520198,0.001592984,0.0005004462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894592,0.009543608,0.0006578873,0.00006092089,0.00003823166,0.0001956753,0.00001223826,0.000002982822,0.00002928542],"genre_scores_gemma":[0.9991574,0.0006663526,0.00005164912,0.0000528134,0.00003670246,0.000005153804,0.000006282488,0.000008819898,0.00001482344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1362718,"threshold_uncertainty_score":0.2558132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00630791018493986,"score_gpt":0.224867099900489,"score_spread":0.2185591897155491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}