{"id":"W2171770874","doi":"10.1128/jvi.06648-11","title":"The Viral Protein Tat Can Inhibit the Establishment of HIV-1 Latency","year":2012,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Jurkat cells; Biology; Virus latency; Virology; Gene silencing; Transactivation; Population; Latency (audio); Intracellular; Viral replication; Virus; Immunology; Gene expression; Cell biology; T cell; Gene; Genetics; Immune system; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002372448,0.0002207524,0.0002013671,0.0000888389,0.0001438356,0.000400677,0.0001761504,0.0002451324,0.0005369802],"category_scores_gemma":[0.0002942154,0.0001064598,0.0001963091,0.00008949968,0.0002043777,0.0001967521,0.0001929764,0.00045656,0.000211681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002033665,"about_ca_system_score_gemma":0.0002196231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005243349,"about_ca_topic_score_gemma":0.000575521,"domain_scores_codex":[0.9997955,0.00006275275,0.00002174223,0.00002774965,0.00004531979,0.00004705417],"domain_scores_gemma":[0.9998121,0.00009239802,0.00003095094,0.00002557055,0.00001644389,0.00002251464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007264798,0.00001880094,0.0001497182,0.000027718,0.000003239812,0.0000240238,0.00001244555,0.00006817732,0.9985729,0.0001549584,0.00002025721,0.0008752217],"study_design_scores_gemma":[0.00001414726,0.0007444731,0.001700472,0.00000910874,0.00001993847,0.0001933798,0.00002352757,0.001876046,0.9927891,0.0001305356,0.002495731,0.00000356616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873573,0.004500521,0.006335486,0.000132331,0.00005286705,0.00002670662,0.000116769,0.00006729486,0.001410892],"genre_scores_gemma":[0.992935,0.001932026,0.003412795,0.0000366403,0.00001731266,0.00002148978,0.0001930982,0.00001485168,0.001436754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005369802,"threshold_uncertainty_score":0.001796365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01100086203386793,"score_gpt":0.24968162404441,"score_spread":0.238680762010542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}