{"id":"W2171862413","doi":"10.3899/jrheum.100551","title":"Biologic DMARD May Be Insufficient to Inhibit CCL20 Pathway in Rheumatoid Arthritis","year":2010,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Rheumatoid arthritis; Etanercept; Tocilizumab; Infliximab; Antirheumatic drugs; CCL20; Biologic Agents; Antirheumatic Agents; Internal medicine; Immunology; Chemokine; Tumor necrosis factor alpha; Inflammation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001524773,0.001154198,0.001672253,0.000446333,0.001275512,0.001279273,0.001264994,0.01536194,0.003340785],"category_scores_gemma":[0.008706724,0.0005274103,0.0006166482,0.0004519504,0.001362162,0.001970818,0.0004343135,0.01271295,0.003407984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001840272,"about_ca_system_score_gemma":0.0006836252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007657328,"about_ca_topic_score_gemma":0.00119328,"domain_scores_codex":[0.9991024,0.0003654355,0.000133977,0.0001118308,0.0001693915,0.0001170739],"domain_scores_gemma":[0.9971533,0.001792229,0.0002510738,0.00008358744,0.0004586077,0.0002611904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008104655,0.0002059286,0.003886973,0.000517365,0.0001037837,0.1049561,0.0002560847,0.0002396561,0.001550209,0.003536531,0.8516054,0.03233157],"study_design_scores_gemma":[0.001453233,0.0008368982,0.01152032,0.0009640396,0.000357198,0.1736193,0.0009421501,0.00482382,0.003099107,0.0138823,0.7883183,0.0001833377],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.008390094,0.0115481,0.0004534402,0.9211295,0.05242191,0.0000372644,0.00008850932,0.0001158425,0.005815349],"genre_scores_gemma":[0.08852288,0.01252234,0.0008399191,0.5211868,0.3613286,0.00006637957,0.00009397326,0.00005215119,0.01538692],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01536194,"threshold_uncertainty_score":0.01335222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02424279937214676,"score_gpt":0.2705765115171547,"score_spread":0.2463337121450079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}