{"id":"W2171872873","doi":"10.1016/s1474-4422(13)70193-5","title":"Combination pharmacotherapy for management of chronic pain: from bench to bedside","year":2013,"lang":"en","type":"review","venue":"The Lancet Neurology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":241,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Medicine; Tolerability; Pharmacotherapy; Fibromyalgia; Chronic pain; Clinical trial; Intensive care medicine; Combination therapy; Neuropathic pain; Drug; Limiting; Pharmacology; Physical therapy; Adverse effect; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000803832,0.001005121,0.002765682,0.00200983,0.0002658483,0.001180518,0.001179716,0.001330285,0.005505612],"category_scores_gemma":[0.001058467,0.0003201478,0.000997255,0.001995015,0.0005634556,0.001346347,0.0007393686,0.002803072,0.001609694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006624032,"about_ca_system_score_gemma":0.001008856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001426045,"about_ca_topic_score_gemma":0.004426608,"domain_scores_codex":[0.9997056,0.0000619279,0.00004038335,0.0000461617,0.0001189805,0.00002690129],"domain_scores_gemma":[0.9993227,0.0004266305,0.00009291748,0.0000141062,0.0001053871,0.00003829642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001589856,0.00009765506,0.0001039036,0.02079048,0.0003102217,0.0001214428,0.00002965718,0.0002329743,0.0007370541,0.001849676,0.02597398,0.949594],"study_design_scores_gemma":[0.0003200476,0.0003683568,0.001788212,0.01984545,0.001062003,0.001954634,0.0001214897,0.0003228572,0.0005168823,0.004364619,0.969277,0.00005855533],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005533334,0.9990683,0.00007712944,0.0002343867,0.0001407258,0.000003491912,0.000008931165,0.000004505006,0.0004071901],"genre_scores_gemma":[0.0006160396,0.9982779,0.0002371146,0.0003653885,0.0002149023,0.000005987473,0.00001595165,0.000001406439,0.0002653522],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005505612,"threshold_uncertainty_score":0.01841813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09613484451347305,"score_gpt":0.3910075314010366,"score_spread":0.2948726868875635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}