{"id":"W2171887903","doi":"10.1016/j.vascn.2011.05.005","title":"Innovation in safety pharmacology testing","year":2011,"lang":"en","type":"editorial","venue":"Journal of Pharmacological and Toxicological Methods","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; L'Alliance Boviteq","funders":"","keywords":"Safety pharmacology; Abuse liability; Medicine; Clinical pharmacology; Drugs of abuse; Pharmacology; Profiling (computer programming); Engineering ethics; Drug; Computer science; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03496696,0.00417291,0.005696407,0.005568937,0.003950526,0.0126808,0.006631754,0.06941997,0.009025482],"category_scores_gemma":[0.08952098,0.002399008,0.00497334,0.002120804,0.00825679,0.009945382,0.005116411,0.06985863,0.006136125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007173713,"about_ca_system_score_gemma":0.00828874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002374593,"about_ca_topic_score_gemma":0.006599853,"domain_scores_codex":[0.9635003,0.008262163,0.005573629,0.004031667,0.01681649,0.001815815],"domain_scores_gemma":[0.8841159,0.0597547,0.005759611,0.003970406,0.03680409,0.009595329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002611014,0.00002082546,0.00003874712,0.0003198293,0.00003871613,0.0002341613,0.0000247654,0.00003864283,0.00007422994,0.0009588504,0.9876089,0.01061625],"study_design_scores_gemma":[0.0001108588,0.00005007222,0.0004141824,0.0009358519,0.000127947,0.0005689206,0.00005323576,0.0002134428,0.0001355711,0.002842858,0.9944983,0.0000486864],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.00003198594,0.01116732,0.000326759,0.1257033,0.861293,0.00001198661,0.00002417995,0.00005538241,0.001386038],"genre_scores_gemma":[0.0004249293,0.004306603,0.0002311441,0.08145861,0.9097959,0.00001546853,0.00001242229,0.00001756438,0.003737296],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.06941997,"threshold_uncertainty_score":0.1849252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07394635309855586,"score_gpt":0.4382979051967004,"score_spread":0.3643515520981446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}