{"id":"W2171891111","doi":"10.1155/2012/686108","title":"Cationic Albumin Nanoparticles for Enhanced Drug Delivery to Treat Breast Cancer: Preparation and <i>In Vitro</i> Assessment","year":2011,"lang":"en","type":"article","venue":"Journal of Drug Delivery","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Faculty of Medicine, McGill University; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Polyethylenimine; Doxorubicin; Biocompatibility; Zeta potential; Cytotoxicity; Cardiotoxicity; Pharmacology; Chemistry; Albumin; Transfection; Nanoparticle; Drug delivery; Human serum albumin; Serum albumin; Bovine serum albumin; Drug; Drug carrier; In vitro; Medicine; Materials science; Nanotechnology; Toxicity; Chemotherapy; Biochemistry; Surgery; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001261337,0.000261789,0.0004778823,0.0002849584,0.0001544796,0.0001136159,0.0003270725,0.00006188166,0.0001043835],"category_scores_gemma":[0.00003807267,0.000238218,0.0001281711,0.0002800487,0.00008783501,0.001106621,0.00009009164,0.0001419498,0.00002840814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004937858,"about_ca_system_score_gemma":0.0005328594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006289374,"about_ca_topic_score_gemma":0.0006239712,"domain_scores_codex":[0.9974273,0.00020681,0.0009532822,0.0003967886,0.0004522472,0.0005635046],"domain_scores_gemma":[0.9980516,0.0002478972,0.0005389302,0.0002787545,0.0005551734,0.0003275776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002608736,0.0003564129,0.0008807838,0.00005428782,0.00001925832,0.00001777791,0.002610753,0.00064943,0.9879397,0.00001351144,0.001229788,0.003619597],"study_design_scores_gemma":[0.001877067,0.0001767403,0.004323354,0.0001456764,0.0001188022,0.0000462248,0.0005714599,0.0006471261,0.9915713,0.0001747622,0.00007568532,0.0002718079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971604,0.0006720911,0.0002492711,0.0006555258,0.0004935724,0.0005704192,0.0001048484,0.00002992684,0.00006389707],"genre_scores_gemma":[0.9930679,0.0002458443,0.005955253,0.0003150177,0.0001862396,0.0001003171,0.000003372126,0.00003145692,0.00009455572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005705982,"threshold_uncertainty_score":0.9714248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01287412995591332,"score_gpt":0.2651760901893994,"score_spread":0.2523019602334861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}