{"id":"W2171891111","doi":"10.1155/2012/686108","title":"Cationic Albumin Nanoparticles for Enhanced Drug Delivery to Treat Breast Cancer: Preparation and <i>In Vitro</i> Assessment","year":2011,"lang":"en","type":"article","venue":"Journal of Drug Delivery","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Faculty of Medicine, McGill University; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Polyethylenimine; Doxorubicin; Biocompatibility; Zeta potential; Cytotoxicity; Cardiotoxicity; Pharmacology; Chemistry; Albumin; Transfection; Nanoparticle; Drug delivery; Human serum albumin; Serum albumin; Bovine serum albumin; Drug; Drug carrier; In vitro; Medicine; Materials science; Nanotechnology; Toxicity; Chemotherapy; Biochemistry; Surgery; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005326043,0.0004725649,0.0003172032,0.0002636864,0.0001805509,0.0002213054,0.0002825673,0.0003708408,0.0007646865],"category_scores_gemma":[0.0003600008,0.0002216699,0.0001787757,0.0002226024,0.0001695224,0.000227083,0.000180264,0.0003064536,0.0004409884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002899742,"about_ca_system_score_gemma":0.0002143289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004985169,"about_ca_topic_score_gemma":0.0007178016,"domain_scores_codex":[0.9998024,0.00007041501,0.000018144,0.00003351992,0.00005084336,0.00002465431],"domain_scores_gemma":[0.99988,0.00003234385,0.00002227258,0.0000109588,0.00003856748,0.00001577384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006331432,0.000028574,0.00003347151,0.00008379421,0.000003765351,0.00002975377,0.00001847683,0.0001709152,0.9962528,0.00007358022,0.0000671191,0.003174321],"study_design_scores_gemma":[0.00001423807,0.0001990691,0.0001789222,0.000003721718,0.000008118435,0.0001025085,0.000003898999,0.000737328,0.9963232,0.00002242988,0.002402022,0.000004596721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8192957,0.01480649,0.1584718,0.0004329312,0.0001500486,0.0005056888,0.0004429334,0.0006554892,0.005238903],"genre_scores_gemma":[0.9087464,0.00620461,0.0767802,0.00016047,0.00003514043,0.000318598,0.0008249005,0.00021581,0.006713977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007646865,"threshold_uncertainty_score":0.002816677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01287412995591332,"score_gpt":0.2651760901893994,"score_spread":0.2523019602334861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}