{"id":"W2171894992","doi":"10.1002/pros.20508","title":"Sulfasalazine‐induced cystine starvation: Potential use for prostate cancer therapy","year":2006,"lang":"en","type":"article","venue":"The Prostate","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Prostate cancer; Medicine; Prostate; Cancer; Starvation; Sulfasalazine; Cystine; Prostate disease; Internal medicine; Oncology; Endocrinology; Cancer research; Biology; Disease; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002239678,0.0002009657,0.0001523236,0.00002822879,0.0001911622,0.00006332347,0.0002369075,0.0001045336,0.00001761992],"category_scores_gemma":[0.00004001025,0.000139558,0.00008252107,0.00009828741,0.0001196845,0.00000829934,0.00008395074,0.0000882643,0.000006404159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002044957,"about_ca_system_score_gemma":0.00009132736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003059109,"about_ca_topic_score_gemma":0.0001630494,"domain_scores_codex":[0.998843,0.00007623531,0.000251041,0.0003612846,0.00009258921,0.0003758908],"domain_scores_gemma":[0.9991614,0.00003085494,0.0001372465,0.0004036886,0.0002334902,0.00003335522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008273186,0.00005503,0.003297429,0.000008292459,0.00007061142,0.000001498609,0.00006298353,0.0003829269,0.986428,0.0001470971,0.006290825,0.002427998],"study_design_scores_gemma":[0.003819236,0.0009704952,0.0325846,0.000008809924,0.00006785344,0.00003166631,0.00004614286,0.0003466202,0.7091773,0.003295708,0.2490926,0.0005589533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937883,0.0007647441,0.0006608957,0.002926111,0.0003950368,0.001112391,0.0002227903,0.00003890009,0.00009085522],"genre_scores_gemma":[0.9911696,0.0003566501,0.0007913938,0.0008877747,0.0006545042,0.0004581377,0.0005635641,0.00004771475,0.005070649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2772507,"threshold_uncertainty_score":0.5691008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02195265638894968,"score_gpt":0.2725527419042882,"score_spread":0.2506000855153385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}