{"id":"W2171944970","doi":"10.1016/s0008-6363(03)00517-0","title":"Tamoxifen and ICI 182,780 negatively influenced cardiac cell growth via an estrogen receptor-independent mechanism","year":2003,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Université de Montréal","funders":"","keywords":"Tamoxifen; Selective estrogen receptor modulator; Endocrinology; Internal medicine; Estrogen receptor; Estrogen; Biology; Cell growth; Agonist; Signal transduction; Kinase; Chemistry; Cancer research; Receptor; Medicine; Cell biology; Cancer; Biochemistry; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002868361,0.0003183845,0.0004375511,0.000158362,0.000380989,0.0001071988,0.000365227,0.0005187776,0.000018127],"category_scores_gemma":[0.0002808862,0.0002983411,0.0005025944,0.0003867994,0.0002674494,0.00002173265,0.0002511835,0.0006428066,0.00008658622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006338008,"about_ca_system_score_gemma":0.0002450625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001434512,"about_ca_topic_score_gemma":7.902979e-7,"domain_scores_codex":[0.9951987,0.001830279,0.0002460826,0.0009571068,0.0009448063,0.0008230355],"domain_scores_gemma":[0.9979106,0.00003962272,0.00004506072,0.0009762128,0.0005384434,0.0004901154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006960092,0.00007865114,0.0007784351,0.0000469586,0.001016948,0.00004103929,0.0001603671,0.00004341815,0.9937463,0.001125911,0.0002160501,0.002676262],"study_design_scores_gemma":[0.0009813613,0.0006364306,0.0003319093,0.00001441915,0.0001069456,0.0000522027,0.0002616863,0.00002362727,0.985081,0.0009380583,0.01118253,0.0003898006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9687874,0.02369191,0.0007607776,0.000016711,0.000163561,0.0008414404,0.00001429967,0.0000332798,0.00569056],"genre_scores_gemma":[0.9954218,0.002817755,0.0008616402,0.000026663,0.000209053,0.0001277572,0.00008657444,0.00007971498,0.0003690774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0266343,"threshold_uncertainty_score":0.9999469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566926558750868,"score_gpt":0.2723898055724717,"score_spread":0.256720539984963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}