{"id":"W2171951110","doi":"10.1152/ajpcell.00553.2009","title":"Silencing of <i>Mustn1</i> inhibits myogenic fusion and differentiation","year":2010,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Myogenin; Myogenesis; MyoD; C2C12; Biology; Myocyte; Myosin; Gene silencing; MYF5; Myogenic regulatory factors; MyoD Protein; RNA interference; Skeletal muscle; Molecular biology; Cell biology; Endocrinology; Genetics; Gene; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001943563,0.0002429297,0.0005816878,0.0001205104,0.000088195,0.000003894242,0.0002886122,0.0001970579,0.00005126977],"category_scores_gemma":[0.00009272522,0.000205574,0.0002115633,0.0001447361,0.0009378785,0.00001398357,0.0001776548,0.0004083093,0.000003422763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005178309,"about_ca_system_score_gemma":0.0001029364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002864451,"about_ca_topic_score_gemma":0.00001411371,"domain_scores_codex":[0.9984689,0.0002251661,0.000532201,0.000360653,0.0001002677,0.0003127609],"domain_scores_gemma":[0.9982486,0.00008739526,0.0009806716,0.0003389836,0.0002240667,0.0001202978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007548499,0.0001962974,0.0005317158,0.00003446165,0.0000779523,3.456898e-7,0.0001044089,0.0001256013,0.9956538,0.00005231323,0.0002963055,0.002171913],"study_design_scores_gemma":[0.001232057,0.002943123,0.09722255,0.00001538964,0.00006110233,0.0000308977,0.0003463704,0.00005357069,0.8963135,0.00118765,0.0003486647,0.0002451591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989451,0.0002875404,0.0000788328,0.00007834003,0.0003803023,0.00009511728,0.000008973791,0.000005766688,0.0001200211],"genre_scores_gemma":[0.9982646,0.0004290518,0.0005079114,0.0003448481,0.0003683537,0.000004488182,0.00003912495,0.00002323354,0.0000184312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09934037,"threshold_uncertainty_score":0.8383064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002925690303331076,"score_gpt":0.2058603356980564,"score_spread":0.2029346453947254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}