{"id":"W2171980237","doi":"10.1016/j.schres.2013.09.005","title":"Effect of COMT Val158Met genotype on nicotine withdrawal-related cognitive dysfunction in smokers with and without schizophrenia","year":2013,"lang":"en","type":"letter","venue":"Schizophrenia Research","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Schizophrenia (object-oriented programming); Nicotine; Catechol-O-methyl transferase; Cognition; Medicine; Nicotine withdrawal; Psychiatry; Nicotine dependence; Psychology; Clinical psychology; Genotype; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.002170608,0.0008277579,0.001096051,0.0006759413,0.0001979961,0.00008809054,0.0005815059,0.001550946,0.0001217418],"category_scores_gemma":[0.0005329498,0.0006410222,0.0001622168,0.0008682367,0.0009928979,0.00001670331,0.000519625,0.004549107,0.0001311165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001131171,"about_ca_system_score_gemma":0.0004791923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003928084,"about_ca_topic_score_gemma":0.0001416241,"domain_scores_codex":[0.9931218,0.00212902,0.0007277672,0.001581284,0.00133281,0.001107336],"domain_scores_gemma":[0.9973198,0.0004970326,0.0003791694,0.0009606284,0.0006520145,0.0001913573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.1815297,0.001535069,0.1069204,0.005231282,0.007758916,0.0001489963,0.000509759,0.0001242172,0.1100801,0.0001033382,0.5021094,0.0839489],"study_design_scores_gemma":[0.1506029,0.1099208,0.02452052,0.01128249,0.001755374,0.0005059384,0.000486736,0.0006951905,0.6461892,0.0002920315,0.04660815,0.007140699],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872577,0.001292524,0.00001415324,0.007422153,0.0002364493,0.002731497,0.00009423771,0.00003526115,0.0009160563],"genre_scores_gemma":[0.991358,0.0005200825,0.0003369137,0.002263339,0.001078096,0.0004344406,0.001452372,0.0002887765,0.002267984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5361091,"threshold_uncertainty_score":0.9997452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01401185292518363,"score_gpt":0.3077885082192683,"score_spread":0.2937766552940846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}