{"id":"W2172029085","doi":"10.1189/jlb.0507305","title":"Antibody ligation of murine Ly-6G induces neutropenia, blood flow cessation, and death via complement-dependent and independent mechanisms","year":2008,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; University of Sheffield; Medical Research Council Canada; British Heart Foundation","keywords":"Biology; Ligation; Antibody; Immunology; Neutropenia; Complement (music); Complement system; Complement component 5; Molecular biology; Chemotherapy; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001751297,0.0001498278,0.0002876531,0.00009188486,0.00008842088,0.000009194864,0.000109492,0.000143943,0.00001312288],"category_scores_gemma":[0.00002762771,0.0001199613,0.00005749465,0.00004101402,0.00006145123,0.00001322702,0.0001018198,0.00009245302,5.451296e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009338417,"about_ca_system_score_gemma":0.00007290203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006166929,"about_ca_topic_score_gemma":0.00002720252,"domain_scores_codex":[0.9990247,0.00008339713,0.0004232066,0.0001968104,0.000115796,0.0001560326],"domain_scores_gemma":[0.999181,0.00001705041,0.0004352158,0.0001181916,0.0001628841,0.00008570666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001497294,0.0002231478,0.06697302,0.00001612727,0.000327102,0.00002307209,0.0000810908,0.000007194833,0.9305653,0.0001329736,0.00001469836,0.001486569],"study_design_scores_gemma":[0.005798063,0.003862235,0.09040087,0.00002704147,0.0002221617,0.001407513,0.0001162806,0.00003426534,0.8962882,0.001293241,0.000341738,0.0002084619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944173,0.002382762,0.00280246,0.00008729402,0.0001203618,0.0001239723,0.00001994502,0.000002315216,0.00004363736],"genre_scores_gemma":[0.9946174,0.003264369,0.001807378,0.00007453981,0.00008632534,0.000002694167,0.0001162685,0.00001096956,0.00002004263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03427715,"threshold_uncertainty_score":0.4891882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01496820345153804,"score_gpt":0.265181674504267,"score_spread":0.250213471052729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}