{"id":"W2172029085","doi":"10.1189/jlb.0507305","title":"Antibody ligation of murine Ly-6G induces neutropenia, blood flow cessation, and death via complement-dependent and independent mechanisms","year":2008,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; University of Sheffield; Medical Research Council Canada; British Heart Foundation","keywords":"Biology; Ligation; Antibody; Immunology; Neutropenia; Complement (music); Complement system; Complement component 5; Molecular biology; Chemotherapy; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001560807,0.0002495692,0.0001917563,0.0001831199,0.00009299089,0.0001920481,0.0001805432,0.0002970412,0.0007588504],"category_scores_gemma":[0.0001278873,0.0001021852,0.0001600411,0.00009218384,0.000194587,0.0001091662,0.0001926139,0.0004624737,0.0002530251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003817684,"about_ca_system_score_gemma":0.0002110677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003259506,"about_ca_topic_score_gemma":0.000544254,"domain_scores_codex":[0.9997924,0.00004970403,0.00001555724,0.00002669515,0.00004825982,0.00006734177],"domain_scores_gemma":[0.999885,0.00002475077,0.00003668351,0.0000152729,0.000007197515,0.00003109924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003159032,0.000119003,0.0002189346,0.0000237085,0.000004350655,0.00008296776,0.0000127577,0.00005995118,0.9968694,0.0001882288,0.00005934852,0.002045424],"study_design_scores_gemma":[0.00009242682,0.002367043,0.006817214,0.000009689062,0.000018506,0.0005532182,0.00001311588,0.0009857352,0.9866637,0.00008522379,0.002390223,0.000003900194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955988,0.00110636,0.001406626,0.00008148677,0.00001922034,0.00004928128,0.0001319004,0.00006529357,0.001541025],"genre_scores_gemma":[0.9959937,0.0005748374,0.001200994,0.00008101796,0.00001035916,0.0000505917,0.0002765723,0.000009442957,0.001802438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007588504,"threshold_uncertainty_score":0.002769947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01496820345153804,"score_gpt":0.265181674504267,"score_spread":0.250213471052729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}