{"id":"W2172031283","doi":"10.1086/500949","title":"Vascular Leakage in Severe Dengue Virus Infections: A Potential Role for the Nonstructural Viral Protein NS1 and Complement","year":2006,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":488,"is_retracted":false,"has_abstract":true,"ca_institutions":"Associated Medical Services","funders":"","keywords":"Anaphylatoxin; Complement system; Dengue fever; Dengue virus; Complement membrane attack complex; Immunology; Antibody; Virology; Lectin pathway; Classical complement pathway; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005479141,0.0002424253,0.0001865268,0.000414122,0.0001561108,0.00030884,0.0001483054,0.0004156824,0.00121607],"category_scores_gemma":[0.001207011,0.00008227655,0.0001460619,0.000199464,0.0003937581,0.0002740042,0.000221945,0.000277235,0.00008880731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002014528,"about_ca_system_score_gemma":0.0001555638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003191957,"about_ca_topic_score_gemma":0.000243295,"domain_scores_codex":[0.9998298,0.00009287646,0.00001231008,0.00001317155,0.00002270185,0.00002924894],"domain_scores_gemma":[0.9996009,0.0001727679,0.0001105684,0.0000220903,0.00004453139,0.00004910014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0122848,0.0005668111,0.4656723,0.002141335,0.0004587537,0.01860241,0.001148506,0.001675577,0.3043079,0.004626817,0.00286008,0.1856548],"study_design_scores_gemma":[0.0003861517,0.00457581,0.8378049,0.0002591239,0.0004470864,0.07560997,0.0007803998,0.005749702,0.05939374,0.006013053,0.008932234,0.00004785245],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835939,0.01321896,0.001283226,0.0005741375,0.00003516435,0.00002439869,0.00003695011,0.00001848218,0.001214891],"genre_scores_gemma":[0.9981532,0.00114866,0.0004140667,0.0000695474,0.00005436835,0.000005179453,0.00003278639,9.057594e-7,0.0001213278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00121607,"threshold_uncertainty_score":0.004068196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003734327425452602,"score_gpt":0.2296296909477199,"score_spread":0.2258953635222673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}