{"id":"W2172066846","doi":"10.1152/ajpgi.00560.2007","title":"CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epithelia","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"WNT5A; Wnt signaling pathway; CDX2; Biology; Internal medicine; Endocrinology; Intestinal epithelium; Calcium-sensing receptor; Receptor; Secretion; Cell biology; Epithelium; Signal transduction; Gene expression; Biochemistry; Medicine; Calcium metabolism; Calcium; Homeobox","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002227589,0.0004314407,0.0003809226,0.0002154501,0.0001248576,0.0003335098,0.0001344417,0.0003133176,0.001693661],"category_scores_gemma":[0.0001280204,0.0001913326,0.0004357745,0.0001290675,0.0001883408,0.0001722512,0.0002273494,0.0004515928,0.0006072049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003666498,"about_ca_system_score_gemma":0.0002077238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008770645,"about_ca_topic_score_gemma":0.001725625,"domain_scores_codex":[0.9997115,0.00005627072,0.00003786162,0.00006085436,0.00006898674,0.00006448345],"domain_scores_gemma":[0.9998673,0.00001862379,0.0000367806,0.00001642444,0.00001506431,0.00004580044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003573782,0.000005702024,0.00006586098,0.00002202741,0.00000237094,0.00002796314,0.000005763535,0.00001101633,0.9996173,0.00001358227,0.00001437862,0.00017812],"study_design_scores_gemma":[0.00002338118,0.0001572847,0.004721703,0.000006901426,0.00001134377,0.0001686498,0.00002512011,0.0007571697,0.9925634,0.00001168444,0.001550015,0.000003286305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921818,0.002485558,0.002555289,0.0002128086,0.0000435464,0.00004493617,0.0005784422,0.0001164662,0.001781181],"genre_scores_gemma":[0.9888,0.0009598435,0.003318714,0.0001258676,0.00001760172,0.00006390208,0.0009423324,0.00003768361,0.005734013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001693661,"threshold_uncertainty_score":0.005665898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01207640784473303,"score_gpt":0.2495802002778448,"score_spread":0.2375037924331118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}