{"id":"W2172068213","doi":"10.1128/mcb.22.12.3970-3980.2002","title":"Protein Kinase C-δ Is a Negative Regulator of Antigen-Induced Mast Cell Degranulation","year":2002,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute; Leibniz-Gemeinschaft; Deutsche Forschungsgemeinschaft","keywords":"Degranulation; Biology; Regulator; Mast cell; Cell biology; Antigen; Protein kinase A; Kinase; Molecular biology; Biochemistry; Immunology; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001460927,0.0006504807,0.0002094503,0.0002645285,0.0002392836,0.0002893114,0.0002932255,0.0001827743,0.000895832],"category_scores_gemma":[0.0001456099,0.0001188493,0.0001553674,0.000185374,0.0002235545,0.0001442216,0.0002319112,0.0005353114,0.0004428791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004728653,"about_ca_system_score_gemma":0.0003382468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005571001,"about_ca_topic_score_gemma":0.0005385287,"domain_scores_codex":[0.9998398,0.00001494576,0.00001624605,0.00003821832,0.00006490228,0.00002584655],"domain_scores_gemma":[0.9999028,0.000007994999,0.00003342712,0.000008474834,0.00002330005,0.00002405036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003778834,0.00004370695,0.0008947815,0.0002789044,0.00001959585,0.0003881575,0.00001584048,0.00009492856,0.9861978,0.0004197105,0.0007155351,0.01055318],"study_design_scores_gemma":[0.000124251,0.0003166911,0.03991198,0.00006541252,0.00009741864,0.003583487,0.00008490273,0.002509639,0.9178627,0.0005519363,0.03486587,0.00002571705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8981435,0.07631898,0.01001724,0.001105963,0.0009874759,0.0001357016,0.001310601,0.0005951417,0.01138538],"genre_scores_gemma":[0.9757249,0.01366555,0.002769295,0.0002248523,0.00007276337,0.00009562029,0.000925413,0.00003202091,0.006489506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000895832,"threshold_uncertainty_score":0.003430843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009719750514536885,"score_gpt":0.1933286376842491,"score_spread":0.1836088871697122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}