{"id":"W2172105693","doi":"10.1126/science.1092009","title":"Editing of CD1d-Bound Lipid Antigens by Endosomal Lipid Transfer Proteins","year":2003,"lang":"en","type":"article","venue":"Science","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":309,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"CD1D; Plant lipid transfer proteins; CD1; Endosome; Lipid metabolism; Cell biology; Chemistry; Antigen; Lipid signaling; Lipid droplet; Membrane lipids; Lipid raft; Biology; Biochemistry; In vitro; Membrane; Cell; Receptor; Antigen-presenting cell; Immunology; Natural killer T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001848226,0.000328243,0.0001439062,0.000179348,0.0001552171,0.0004043734,0.0001309565,0.0002068484,0.00101986],"category_scores_gemma":[0.0002462157,0.0001228502,0.0001646602,0.00007089396,0.0002369306,0.000280149,0.0003609987,0.0004897787,0.0004842394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003394407,"about_ca_system_score_gemma":0.0001017976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000166456,"about_ca_topic_score_gemma":0.0002051498,"domain_scores_codex":[0.9998853,0.00002481611,0.000006130608,0.00002342642,0.00002814088,0.00003220866],"domain_scores_gemma":[0.9998865,0.00002923916,0.00003085707,0.00001931806,0.00001015433,0.000023969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005026058,0.00000583427,0.0001503307,0.00001171172,0.000001835428,0.00004966115,0.00001153929,0.00005476873,0.9981595,0.0001967481,0.00001731661,0.001290616],"study_design_scores_gemma":[0.000007334466,0.00004405866,0.000938826,0.000002820503,0.000005363984,0.0002212422,0.00001933399,0.0007477403,0.9961467,0.0001047565,0.001759271,0.000002509866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993687,0.0006201887,0.004258715,0.00005570284,0.0000145288,0.000009631155,0.00004418787,0.00004178488,0.001268157],"genre_scores_gemma":[0.9954765,0.0003476463,0.002087019,0.00002771423,0.00000711294,0.000009014378,0.0001312339,0.00002252098,0.001891071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00101986,"threshold_uncertainty_score":0.00341177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01028857225587239,"score_gpt":0.2273467701485358,"score_spread":0.2170581978926634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}