{"id":"W2172105693","doi":"10.1126/science.1092009","title":"Editing of CD1d-Bound Lipid Antigens by Endosomal Lipid Transfer Proteins","year":2003,"lang":"en","type":"article","venue":"Science","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":309,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"CD1D; Plant lipid transfer proteins; CD1; Endosome; Lipid metabolism; Cell biology; Chemistry; Antigen; Lipid signaling; Lipid droplet; Membrane lipids; Lipid raft; Biology; Biochemistry; In vitro; Membrane; Cell; Receptor; Antigen-presenting cell; Immunology; Natural killer T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004199271,0.00009643982,0.0001281288,0.0001025882,0.0003242866,0.00002087998,0.000186098,0.00007845866,0.001346774],"category_scores_gemma":[0.0001940646,0.0000852676,0.00005522952,0.0003059354,0.0006218081,0.0002962976,0.00001629977,0.0001883445,0.0002841727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003000228,"about_ca_system_score_gemma":0.0001113589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002754524,"about_ca_topic_score_gemma":0.000004236504,"domain_scores_codex":[0.9990633,0.00007880148,0.0002232132,0.0002529623,0.00006470138,0.0003170775],"domain_scores_gemma":[0.9996299,0.0000323698,0.00005339162,0.0001800009,0.00008498312,0.0000193155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001692786,0.00006702237,0.0003439601,0.000005081535,0.000007907569,2.056161e-7,0.0002609049,0.000001131622,0.995488,0.001085614,0.001909801,0.0008134805],"study_design_scores_gemma":[0.0002694647,0.0001440407,0.0003114188,0.00001357672,0.000004387865,0.00002684769,0.000238485,0.000002475278,0.7537315,0.000009441917,0.2451816,0.00006667638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9659185,0.0006226572,0.003089562,0.0001497953,0.009050227,0.0002672948,0.000006519623,0.00004757088,0.02084781],"genre_scores_gemma":[0.9910385,0.00002499711,0.00005614545,0.000105605,0.00004098435,0.000008376033,0.000008074952,0.00000593647,0.008711363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2432719,"threshold_uncertainty_score":0.9995661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01028857225587239,"score_gpt":0.2273467701485358,"score_spread":0.2170581978926634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}