{"id":"W2172185157","doi":"10.1139/cjpp-2013-0012","title":"Leptin-activity blockers: development and potential use in experimental biology and medicine","year":2013,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Leptin; Adipokine; Immune system; Adipose tissue; Cachexia; Medicine; Disease; Biology; Endocrinology; Internal medicine; Carcinogenesis; In vivo; Immunology; Cancer; Obesity","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006324795,0.001100015,0.001614782,0.002848247,0.0003145423,0.00109092,0.001020449,0.001270813,0.002631657],"category_scores_gemma":[0.0004659416,0.0004120332,0.0005604225,0.001759836,0.0006536455,0.001369976,0.0007826582,0.002410848,0.002414253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005706428,"about_ca_system_score_gemma":0.0007115649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005800287,"about_ca_topic_score_gemma":0.000996031,"domain_scores_codex":[0.9997801,0.00003286821,0.00002689773,0.0000437739,0.00009126674,0.00002499099],"domain_scores_gemma":[0.9997653,0.00009260197,0.0000364784,0.00001166179,0.00005728671,0.00003664835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000157057,0.0002010349,0.0001651604,0.009761884,0.00007244087,0.0006232517,0.0000893758,0.0003611341,0.02187406,0.007102861,0.01019975,0.9493921],"study_design_scores_gemma":[0.00008154059,0.0004079741,0.001026221,0.001766673,0.000121131,0.003059051,0.0000670748,0.0002160822,0.008960134,0.003958907,0.9802797,0.00005555968],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005775609,0.9961802,0.0008538141,0.0001898186,0.0001564672,0.0000186737,0.0000294185,0.00002187528,0.001972179],"genre_scores_gemma":[0.002308502,0.9949398,0.001224946,0.0002121572,0.0001234601,0.00003393843,0.00006095049,0.000005030401,0.001091283],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002848247,"threshold_uncertainty_score":0.008803785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07673307170883134,"score_gpt":0.3600566197519774,"score_spread":0.2833235480431461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}