{"id":"W2172251621","doi":"10.3390/s90705351","title":"Multivalent Anchoring and Oriented Display of Single-Domain Antibodies on Cellulose","year":2009,"lang":"en","type":"article","venue":"Sensors","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Institute for Biological Sciences; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pentamer; Biosensor; Avidity; Cellulose; Chemistry; Antibody; Phage display; Single-domain antibody; Bispecific antibody; Combinatorial chemistry; Biochemistry; Peptide; Biology; Monoclonal antibody; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001091371,0.0001379411,0.0002694326,0.000119275,0.00005608391,0.000006594419,0.00003911863,0.00005048986,0.00003293238],"category_scores_gemma":[0.00007423636,0.000100154,0.00007174371,0.0001220572,0.0001339242,0.00002367745,0.00002609761,0.0001502898,0.00001613323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002387219,"about_ca_system_score_gemma":0.00001316884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003918509,"about_ca_topic_score_gemma":0.000003092994,"domain_scores_codex":[0.9989554,0.00004010074,0.0002011475,0.0002214865,0.0003227238,0.0002591065],"domain_scores_gemma":[0.9994832,0.00009894501,0.00004893371,0.0001556571,0.00006742803,0.0001458866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002653801,0.001091754,0.06947406,0.0003583492,0.00012321,0.0004260829,0.00218466,0.00002985652,0.8894495,0.007077023,0.0007857972,0.02634594],"study_design_scores_gemma":[0.002667256,0.003562453,0.4823166,0.0008111011,0.00005927358,0.00009759267,0.0007383226,0.001010251,0.4871279,0.0004942412,0.02075822,0.0003567613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896873,0.0003198197,0.000006954619,0.001321604,0.00006328269,0.000190315,0.00001362661,0.00002371852,0.00837334],"genre_scores_gemma":[0.9940211,0.0001676586,0.0007981445,0.0001193387,0.0001334415,8.862028e-7,0.00001194959,0.000009811446,0.0047377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4128426,"threshold_uncertainty_score":0.4084162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02643265025345029,"score_gpt":0.3032441867855512,"score_spread":0.2768115365321009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}