{"id":"W2172369043","doi":"10.1667/0033-7587(2000)153[0813:rtwaws]2.0.co;2","title":"Radioprotective Thiolamines WR-1065 and WR-33278 Selectively Denature Nonhistone Nuclear Proteins","year":2000,"lang":"en","type":"article","venue":"Radiation Research","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Denaturation (fissile materials); Nuclear protein; Nuclear matrix; Chemistry; Biophysics; Biochemistry; Nucleoprotein; Differential scanning calorimetry; Non-histone protein; Molecular biology; DNA; Chromatin; Biology; Nuclear chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005475798,0.0001415963,0.0001375679,0.0001204016,0.0003706623,0.00007654317,0.0001521687,0.0002284332,0.0002558181],"category_scores_gemma":[0.000120688,0.0001373121,0.00005656543,0.0002898336,0.0001377951,0.000009685619,0.00006786855,0.0003561246,0.00004757016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009624875,"about_ca_system_score_gemma":0.0001341975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001705458,"about_ca_topic_score_gemma":0.00007699421,"domain_scores_codex":[0.9984085,0.0002321069,0.0001469299,0.000472797,0.0003688145,0.0003708715],"domain_scores_gemma":[0.9993138,0.00002765649,0.00003560425,0.0002701328,0.000225484,0.0001272777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003683698,0.0001396895,0.0007656655,0.00003831697,0.00008842559,0.00001034863,0.0004991487,0.00006707171,0.9338525,0.0002384848,0.005403449,0.05852854],"study_design_scores_gemma":[0.002539799,0.002369652,0.1398741,0.00003770049,0.00002898924,0.0001200538,0.0004963146,0.001405681,0.4585081,0.0005728885,0.3932902,0.0007565834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930111,0.001463049,0.0000840288,0.0007664734,0.00002985499,0.0009305112,0.00004540751,0.00001911191,0.003650496],"genre_scores_gemma":[0.9950998,0.0007885583,0.0005202375,0.0001348437,0.0002838667,0.000110697,0.00005165503,0.00002438124,0.002985969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4753444,"threshold_uncertainty_score":0.5599426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01402819182778818,"score_gpt":0.314552393382417,"score_spread":0.3005242015546288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}