{"id":"W2172767004","doi":"10.1158/2159-8290.cd-15-0987","title":"T Regulatory Cells Gone Bad: An Oncogenic Immune Response against Enterotoxigenic <i>B. fragilis</i> Infection Leads to Colon Cancer","year":2015,"lang":"en","type":"letter","venue":"Cancer Discovery","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Immune system; Colorectal cancer; Biology; Cancer; Enterotoxigenic Escherichia coli; Immunology; Gene; Genetics; Enterotoxin; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001091272,0.0006303546,0.0006642931,0.0003300209,0.0009217871,0.001469903,0.000581664,0.008587494,0.00670932],"category_scores_gemma":[0.003993693,0.0002784379,0.0005584059,0.0001988952,0.00112619,0.0008366195,0.0004211437,0.009435951,0.00551396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00207291,"about_ca_system_score_gemma":0.0006368801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008308704,"about_ca_topic_score_gemma":0.001453125,"domain_scores_codex":[0.9991856,0.000254553,0.00006862992,0.0001286481,0.0002353916,0.000127185],"domain_scores_gemma":[0.9986186,0.0007061735,0.00009935505,0.00009965454,0.0002480758,0.000228048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008114418,0.0001901881,0.001681833,0.0001385666,0.00003928255,0.004485399,0.00007286225,0.0002272469,0.00911801,0.004976691,0.921248,0.05701063],"study_design_scores_gemma":[0.0007718733,0.00104598,0.00594566,0.0002225598,0.00008211703,0.007362096,0.0002516198,0.001644246,0.01106,0.01036628,0.9611843,0.00006328682],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.009474031,0.009056234,0.0006273001,0.9367046,0.03118788,0.0000580766,0.0003151369,0.0002508435,0.01232596],"genre_scores_gemma":[0.1178003,0.01272893,0.001337491,0.7218963,0.08214283,0.0001993143,0.0003929833,0.00008339649,0.06341848],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.008587494,"threshold_uncertainty_score":0.02244484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01462267793477046,"score_gpt":0.2884545714435541,"score_spread":0.2738318935087836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}