{"id":"W2173088720","doi":"10.1139/bcb-2012-0065","title":"Oligomerization and hemolytic properties of the C-terminal domain of pyolysin, a cholesterol-dependent cytolysin","year":2013,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Cytolysin; Membrane; Monomer; Streptolysin; Biophysics; Oligomer; Chemistry; Toxin; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001155688,0.0002330623,0.0001219507,0.000167557,0.0001101566,0.0001985256,0.0001003513,0.0001921912,0.0004681835],"category_scores_gemma":[0.0002444213,0.00010554,0.0001766312,0.0001242665,0.0002082045,0.0001664927,0.0001779846,0.0003663738,0.0001722113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002168635,"about_ca_system_score_gemma":0.0001223982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005285061,"about_ca_topic_score_gemma":0.000315556,"domain_scores_codex":[0.9998778,0.0000286508,0.00001094616,0.0000244337,0.00003407939,0.00002400997],"domain_scores_gemma":[0.9998494,0.0000434358,0.0000392625,0.00001969034,0.00001765936,0.00003059487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000357772,0.00002165926,0.0004515518,0.000008904713,0.000003770385,0.00002352445,0.00001758247,0.00004839316,0.9990844,0.00004163877,0.000006321329,0.000256477],"study_design_scores_gemma":[0.00001131976,0.0003450712,0.02321878,0.000006149606,0.00002270966,0.0004252159,0.00006366245,0.001895569,0.9731243,0.00008819062,0.0007909531,0.000007969688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987739,0.0002087973,0.0006340339,0.00001193912,0.000001972392,0.000004620683,0.00005989919,0.000006131764,0.0002987246],"genre_scores_gemma":[0.9975216,0.000174522,0.0009055417,0.00002027038,0.000002683624,0.0000131522,0.0004734863,0.000005734265,0.0008829033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005285061,"threshold_uncertainty_score":0.001573384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009395668912994776,"score_gpt":0.2224407105854115,"score_spread":0.2130450416724167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}