{"id":"W2173155709","doi":"10.1111/bjh.13810","title":"Laboratory measurement of the direct oral anticoagulants","year":2015,"lang":"en","type":"review","venue":"British Journal of Haematology","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Rivaroxaban; Edoxaban; Apixaban; Dabigatran; Medicine; Anticoagulant; Discovery and development of direct thrombin inhibitors; Pharmacology; Coagulation; Direct thrombin inhibitor; Drug; Warfarin; Thrombin; Internal medicine; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001680212,0.0001854644,0.003571194,0.0001758961,0.00003881266,0.00001672095,0.000254115,0.0002049207,0.00005486049],"category_scores_gemma":[0.0009456982,0.0001274023,0.0007693309,0.0003039313,0.0001162814,0.00005299755,0.00009016007,0.0003395106,0.00001132575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001013137,"about_ca_system_score_gemma":0.000880924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001118869,"about_ca_topic_score_gemma":0.00001342395,"domain_scores_codex":[0.9971854,0.0005087174,0.00125788,0.0001268747,0.0007454517,0.0001756714],"domain_scores_gemma":[0.9970994,0.00008147424,0.001619564,0.00021985,0.0008773241,0.000102408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000702318,0.00005890231,0.002196948,0.01975058,0.00255308,0.008857153,0.00002796892,0.000001103978,0.000003642437,0.0001545718,0.05832399,0.9080018],"study_design_scores_gemma":[0.0005909615,0.00007802971,0.0002409546,0.01693979,0.002974414,0.0305451,0.00001278694,3.407221e-7,0.000007713244,0.00002580491,0.9484808,0.0001033038],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000443135,0.9970716,0.000007763128,0.0001726467,0.001139778,0.0004251701,0.00001936923,0.000007802368,0.0007127423],"genre_scores_gemma":[0.0009768902,0.9982225,0.0001520852,0.00004005168,0.0003878701,7.975664e-7,0.000003904948,0.00002835905,0.0001875271],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9078985,"threshold_uncertainty_score":0.5195314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1989839693630975,"score_gpt":0.3966434147564193,"score_spread":0.1976594453933218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}