{"id":"W2173326641","doi":"10.1081/ncn-120026634","title":"<i>Cyclo</i>Saligenyl Pronucleotides of 5-Iodo and 5-Trifluoromethyl-1-(2-deoxy-β-<scp>D</scp>-ribofuranosyl)-2,4-difluorobenzene Mimics of Thymidine: Synthesis and Evaluation of this Pronucleotide Monophosphate Delivery System for Compounds with Potential Anticancer Activity","year":2003,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Diastereomer; Stereochemistry; Substituent; Chemistry; Trifluoromethyl; Thymidine; In vitro; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009244132,0.0003482085,0.0001120272,0.00007451294,0.00006862838,0.0001417513,0.0001569704,0.0002009365,0.001124334],"category_scores_gemma":[0.0001197153,0.0001069463,0.0001132379,0.00008498737,0.0001283155,0.0001849337,0.0001396679,0.0002776058,0.0003179989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001588901,"about_ca_system_score_gemma":0.0002189223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006042427,"about_ca_topic_score_gemma":0.000653424,"domain_scores_codex":[0.9999098,0.00001635619,0.000008242231,0.00002665712,0.00001878353,0.00002011326],"domain_scores_gemma":[0.9999293,0.00001115252,0.00002981815,0.000005236292,0.000008706125,0.00001577104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009370609,0.000008523348,0.00006565489,0.00003715319,0.000002263564,0.00002905186,0.000009163509,0.0001022017,0.9976277,0.0001354714,0.00001873228,0.001870418],"study_design_scores_gemma":[0.000009011205,0.0002986701,0.0003699528,0.000002964023,0.000004892668,0.00009504645,0.000006127353,0.0002412514,0.9971915,0.00001407016,0.001763419,0.00000306069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841628,0.0013526,0.009596969,0.00004722996,0.00004139077,0.00008410061,0.0002813048,0.00009691135,0.004336728],"genre_scores_gemma":[0.988809,0.000677672,0.007623716,0.00004911259,0.00000941903,0.00005348629,0.0003911745,0.00002113564,0.002365135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001124334,"threshold_uncertainty_score":0.003761232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01227741570135653,"score_gpt":0.2440015017879634,"score_spread":0.2317240860866069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}