{"id":"W2173518829","doi":"10.1038/mt.2015.185","title":"Gene Editing and Germ-line Intervention: The Need for Novel Responses to Novel Technologies","year":2015,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Wellcome Trust","keywords":"CRISPR; Scopus; Genome editing; Germline; Genetics; Gene; Biology; Political science; MEDLINE; Law","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02943197,0.00121717,0.002379777,0.002370732,0.001676321,0.008156083,0.003169228,0.01394767,0.02038314],"category_scores_gemma":[0.04409157,0.0006332208,0.001704695,0.001365032,0.01225401,0.02168514,0.006926403,0.02434674,0.005338552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003330141,"about_ca_system_score_gemma":0.007441632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001021954,"about_ca_topic_score_gemma":0.001605737,"domain_scores_codex":[0.9880591,0.004633331,0.0009466212,0.001330393,0.004110502,0.0009200079],"domain_scores_gemma":[0.9345346,0.04776761,0.002710407,0.004052994,0.007851248,0.003083096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005225918,0.0003326448,0.0008509126,0.008183744,0.0002709172,0.00126454,0.001200129,0.000626703,0.005132702,0.1541886,0.3042834,0.5231431],"study_design_scores_gemma":[0.0001008358,0.0003151534,0.0005395254,0.003848465,0.00007659522,0.001292665,0.001499404,0.000281519,0.002168534,0.115719,0.8740562,0.0001021045],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001130043,0.3286245,0.01057053,0.6352921,0.01538909,0.0000726028,0.0001659468,0.0002461681,0.008509136],"genre_scores_gemma":[0.02848977,0.5102876,0.023995,0.3966838,0.0282396,0.0004179625,0.0004525096,0.0003686252,0.01106516],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02943197,"threshold_uncertainty_score":0.155653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02531575537985657,"score_gpt":0.3213336571325398,"score_spread":0.2960179017526832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}