{"id":"W2174244738","doi":"10.4141/cjas2011-086","title":"Expressions of matrix metalloproteinases and their inhibitor are modified by beta-adrenergic agonist Ractopamine in skeletal fibroblasts and myoblasts","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Animal Science","topic":"Pharmacological Effects and Assays","field":"Agricultural and Biological Sciences","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Ministry of Agriculture, Food and Rural Affairs; Ontario Ministry of Agriculture, Food and Rural Affairs; University of Guelph","keywords":"Ractopamine; Myocyte; C2C12; Matrix metalloproteinase; Extracellular matrix; Skeletal muscle; Chemistry; Endocrinology; Internal medicine; Cell culture; Agonist; Biology; Myogenesis; Receptor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006220777,0.0001242606,0.000254717,0.00005631529,0.000216096,0.00007220988,0.0002372214,0.00005196908,0.00007902852],"category_scores_gemma":[0.0001420611,0.00004576935,0.00005039086,0.0003874309,0.0005591777,0.0004846292,0.00005476518,0.0001500924,5.191859e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003414818,"about_ca_system_score_gemma":0.00007139632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001063595,"about_ca_topic_score_gemma":0.001587689,"domain_scores_codex":[0.9989483,0.00006650473,0.0002591414,0.0001527515,0.000167745,0.0004055036],"domain_scores_gemma":[0.998742,0.0001449529,0.0002168515,0.0000261535,0.00007320143,0.0007968146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001705651,0.00003363725,0.004424561,0.00000526291,0.000003144756,0.000009457368,0.00006081022,0.0000032731,0.9924116,0.00009657743,0.0001089065,0.002825676],"study_design_scores_gemma":[0.0003499663,0.001171707,0.7738996,0.0001397505,0.00001577567,0.000108104,0.0005484039,0.0001316133,0.2204276,0.0001079029,0.002855839,0.0002437867],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972323,0.00185095,0.000001443623,0.0006092935,0.00005625296,0.00008948145,0.00006213014,0.000002386293,0.00009573857],"genre_scores_gemma":[0.9997497,0.00003451107,0.00004739899,0.00005233258,0.00009795827,0.00000174403,0.000001124534,7.636553e-7,0.00001451925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.771984,"threshold_uncertainty_score":0.2060313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01891131292386998,"score_gpt":0.2439483029412028,"score_spread":0.2250369900173328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}