{"id":"W2174267452","doi":"10.4049/jimmunol.1501140","title":"Priming of Qualitatively Superior Human Effector CD8+ T Cells Using TLR8 Ligand Combined with FLT3 Ligand","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Agence Nationale de la Recherche; Wellcome Trust","keywords":"Priming (agriculture); Effector; Ligand (biochemistry); CD8; Chemistry; Cytotoxic T cell; Cell biology; Biology; Immunology; Molecular biology; Immune system; Biochemistry; Receptor; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002311489,0.0002998625,0.0008938441,0.0002868436,0.0002880806,0.00001839534,0.0007034243,0.0002657427,0.00005061965],"category_scores_gemma":[0.0001970997,0.0001804234,0.0001687771,0.0002328817,0.001139156,0.0002128873,0.0001173395,0.0006849385,0.0000340232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000892938,"about_ca_system_score_gemma":0.0004208677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002013892,"about_ca_topic_score_gemma":0.000008082132,"domain_scores_codex":[0.996493,0.001895769,0.0009284713,0.0001402597,0.0001080725,0.0004343919],"domain_scores_gemma":[0.9970617,0.0009355074,0.001072127,0.0004014806,0.0005011235,0.00002809388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01409895,0.0002208718,0.0003262803,0.0000232041,0.001362568,0.00001281339,0.0110962,0.00003730435,0.9720446,0.0001093194,0.0002015847,0.0004662758],"study_design_scores_gemma":[0.007179161,0.008158769,0.002980809,0.0002790143,0.0002650827,0.001220912,0.005757635,0.000001708627,0.9714144,0.0001001289,0.002418851,0.0002235188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791169,0.01923535,0.0002907366,0.0001985447,0.0007907393,0.000261818,0.000008890053,0.00001614357,0.00008088176],"genre_scores_gemma":[0.9986987,0.0003256986,0.0002414441,0.00007551608,0.00003451484,0.000002318205,0.000004705667,0.00003845547,0.0005787073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01958174,"threshold_uncertainty_score":0.7357452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03480996594086598,"score_gpt":0.289970258765011,"score_spread":0.255160292824145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}