{"id":"W2174644229","doi":"10.1371/journal.pone.0138738","title":"Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett’s Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Health and Medical Research Council; Australian Research Council; Wellcome Trust; Francis Crick Institute; National Cancer Institute; National Institutes of Health; Cancer Research UK; National Institute for Health and Care Research; Robert Wood Johnson Foundation","keywords":"Oxytocin receptor; Aromatase; Estrogen receptor alpha; Biology; Internal medicine; Endocrinology; Oxytocin; Estrogen receptor; Genetics; Medicine; Breast cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009136315,0.00114747,0.0032605,0.00375009,0.0006420724,0.001466722,0.0008466633,0.001044211,0.002123895],"category_scores_gemma":[0.01461872,0.0008726399,0.006539807,0.00556917,0.0004115465,0.0004095917,0.001389619,0.0005261257,0.0002451873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004991241,"about_ca_system_score_gemma":0.0006666893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01368452,"about_ca_topic_score_gemma":0.01343617,"domain_scores_codex":[0.9898706,0.005957185,0.001036777,0.001795396,0.0009289276,0.0004111669],"domain_scores_gemma":[0.9893311,0.0048181,0.00205796,0.002109803,0.001122555,0.0005603766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01161141,0.0000557762,0.8439532,0.001401085,0.1253964,0.0004881512,0.0003740511,0.0007092203,0.003424508,0.0001366681,0.001411972,0.01103749],"study_design_scores_gemma":[0.001102009,0.0007294987,0.8780738,0.0003080553,0.1153968,0.0007058359,0.00026035,0.0006302426,0.0004643729,0.0002030601,0.002075736,0.00005029347],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9498582,0.03756236,0.004667466,0.0002393616,0.0001137076,0.0001331176,0.006475681,0.00008882752,0.0008613594],"genre_scores_gemma":[0.9912805,0.003103312,0.001230717,0.00008812644,0.00006224578,0.0001499046,0.003732324,0.00004759146,0.0003053743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01368452,"threshold_uncertainty_score":0.04831803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05579749953475659,"score_gpt":0.26672234448118,"score_spread":0.2109248449464234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}