{"id":"W2174790513","doi":"10.1021/jo040292c","title":"Reactions of Indole Derivatives with Oxiranes and Aziridines on Silica. Synthesis of β-Carbolin-1-one Mimic of Pancratistatin","year":2005,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Brock University","keywords":"Chemistry; Aziridine; Epoxide; Indole test; Silica gel; Yield (engineering); Lewis acids and bases; Ring (chemistry); Organic chemistry; Catalysis; Polymer chemistry; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103249,0.0002781916,0.0001447261,0.000124719,0.0001099981,0.0001059558,0.0002076652,0.0001529533,0.0007351997],"category_scores_gemma":[0.0001083355,0.0001272931,0.0001554558,0.0001107968,0.0001537083,0.0001667644,0.0001456396,0.0001762077,0.0003336612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001924903,"about_ca_system_score_gemma":0.0001352792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003833621,"about_ca_topic_score_gemma":0.0009367704,"domain_scores_codex":[0.999925,0.00001122353,0.000004989902,0.00001603948,0.0000224731,0.0000202001],"domain_scores_gemma":[0.9999337,0.0000140889,0.00002116814,0.000008442054,0.000008378291,0.00001417337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005035034,0.000006640388,0.00004978539,0.00004457017,0.000004568814,0.00005334361,0.00002170797,0.0001117735,0.9986318,0.00007573555,0.00001800279,0.0009317049],"study_design_scores_gemma":[0.00001009497,0.0002840145,0.0006552159,0.000003278025,0.000007090419,0.0001278173,0.000009005903,0.0002618791,0.9971124,0.00002345107,0.001502108,0.000003539273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856557,0.002556697,0.003414026,0.000041032,0.00003222685,0.00006306794,0.0001413427,0.00007687963,0.008018998],"genre_scores_gemma":[0.9928491,0.00142593,0.002942097,0.00002461963,0.00001055883,0.00002176155,0.0001800183,0.00001439945,0.00253151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007351997,"threshold_uncertainty_score":0.002459466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008902408781093421,"score_gpt":0.2079868774421477,"score_spread":0.1990844686610543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}